Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 4/20 | 0.72 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.72 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.72 |
| ▸ | RXRA | P19793 | 5/20 | 0.71 |
| ▸ | RXRB | P28702 | 5/20 | 0.71 |
| ▸ | RAB9A | P51151 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.66 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.64 |
| ▸ | MAOB | P27338 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.62 |
| ▸ | PTPRC | P08575 | 1/20 | 0.62 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254794 | 1.00 | NR4A2 (0.72) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL8134318 | 0.91 | NR4A2 (0.85) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL29185186 | 0.85 | NR4A2 (0.60) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL6830467 | 0.84 | NR4A2 (1.00) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL4059143 | 0.84 | NR4A2 (1.00) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL228477 | 0.84 | NR4A2 (1.00) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL1750167 | 0.84 | NR4A2 (0.86) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL6654887 | 0.83 | SRD5A2 (0.77) | NR4A2NR4A1NR4A3RAB9ASMN1; SMN2 | |
| SCHEMBL31542030 | 0.83 | MAOB (0.80) | RAB9ASMN1; SMN2MAOBGAAMAPT | |
| SCHEMBL5121663 | 0.83 | MAOB (0.80) | RAB9ASMN1; SMN2MAOBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012031298-A2 | ETHYNYLBENZENE DERIVATIVES | DUKE UNIVERSITY (US) | 2012-03-08 | — | — | WO | disclosed |