Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | CSF1R | P07333 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24988903 | 0.89 | NPY5R (0.38) | EGFRCSF1RMEN1KMT2A | |
| SCHEMBL30224912 | 0.88 | EGFR (0.38) | EGFRCSF1RMEN1KMT2A | |
| SCHEMBL27237584 | 0.87 | EGFR (0.31) | EGFRCSF1R | |
| SCHEMBL30224808 | 0.86 | EGFR (0.32) | EGFRCSF1R | |
| SCHEMBL29185320 | 0.86 | EGFR (0.32) | EGFRCSF1R | |
| SCHEMBL30224766 | 0.82 | NPY5R (0.37) | EGFRCSF1RMEN1KMT2AADORA2A | |
| SCHEMBL30224906 | 0.82 | ALDH1A1 (0.38) | EGFRCSF1RALDH1A1 | |
| SCHEMBL30224929 | 0.81 | XDH (0.37) | — | |
| SCHEMBL24988860 | 0.80 | NPY5R (0.43) | MEN1KMT2AADORA2AADORA2BADORA1 | |
| SCHEMBL24989609 | 0.79 | EGFR (0.38) | EGFRCSF1RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794917-A | Novel indole derivatives, pharmaceutical compositions containing the same and uses thereof | 水疗免疫疗法有限公司 | 2024-03-29 | — | — | CN | disclosed |
| WO-2023013994-A1 | NOVEL INDOLE DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 주식회사 미토이뮨테라퓨틱스 | 2023-02-09 | — | — | WO | disclosed |