Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30364099 | 0.75 | MAPKAPK2 (0.36) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL26522281 | 0.75 | MAPKAPK2 (0.36) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29159708 | 0.72 | KDM4E (0.37) | PARP1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL26522301 | 0.72 | ALDH1A1 (0.34) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30363764 | 0.69 | AAK1 (0.35) | HPGD | |
| SCHEMBL26532853 | 0.69 | AAK1 (0.35) | HPGD | |
| SCHEMBL27221599 | 0.66 | MAPKAPK2 (0.36) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29010984 | 0.65 | HDAC3 (0.38) | PARP1HPGD | |
| SCHEMBL27221553 | 0.65 | XDH (0.34) | XDHHPGDSLC22A12 | |
| SCHEMBL28947251 | 0.64 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116234797-A | Heterocyclic inhibitors of TEAD for the treatment of cancer | 基因泰克公司 | 2023-06-06 | — | — | CN | disclosed |