Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | ITGAL | P20701 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 2/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30949613 | 0.80 | HTR2A (0.43) | HTR2AHTR2CHTR2BLMNAHTT | |
| SCHEMBL20741822 | 0.80 | HTR2A (0.43) | HTR2AHTR2CHTR2BLMNAHTT | |
| SCHEMBL30364067 | 0.79 | HTR2A (0.40) | HTR2AHTR2CHTR2B | |
| SCHEMBL29185346 | 0.79 | HTR2A (0.40) | HTR2AHTR2CHTR2B | |
| SCHEMBL19765002 | 0.74 | LMNA (0.39) | HTR2AHTR2CHTR2BLMNAHTT | |
| SCHEMBL30364094 | 0.71 | ITGB2 (0.44) | LMNAHTTITGB2ICAM1ITGAL | |
| SCHEMBL10159205 | 0.67 | MAPT (0.39) | HTR2AHTR2CHTR2BLMNAHTT | |
| SCHEMBL29185355 | 0.66 | — | — | |
| SCHEMBL25208990 | 0.64 | HTR2C (0.36) | HTR2AHTR2CHTR2BLMNAHTT | |
| SCHEMBL25064286 | 0.63 | HTR2A (0.35) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116234797-A | Heterocyclic inhibitors of TEAD for the treatment of cancer | 基因泰克公司 | 2023-06-06 | — | — | CN | disclosed |