Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.37 |
| ▸ | ITGAL | P20701 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 6/20 | 0.35 |
| ▸ | CRHBP | P24387 | 2/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30329793 | 0.77 | LMNA (0.38) | LMNAHTTMAPTBLMITGB2 | |
| SCHEMBL30949613 | 0.77 | HTR2A (0.43) | LMNAHTTMAPTBLMITGB2 | |
| SCHEMBL20741822 | 0.77 | HTR2A (0.43) | LMNAHTTMAPTBLMITGB2 | |
| SCHEMBL20729436 | 0.77 | ALDH1A1 (0.39) | LMNAHTTMAPTITGB2ICAM1 | |
| SCHEMBL2026290 | 0.77 | LMNA (0.38) | LMNAHTTMAPTBLMITGB2 | |
| SCHEMBL25166334 | 0.77 | LMNA (0.38) | LMNAHTTMAPTBLMITGB2 | |
| SCHEMBL7473749 | 0.77 | ADRA2A (0.44) | LMNAHTTMAPTBLMITGB2 | |
| SCHEMBL25844876 | 0.76 | AOC3 (0.46) | LMNAHTTMAPTBLMITGB2 | |
| SCHEMBL17397871 | 0.74 | KDM4E (0.40) | LMNAHTTMAPTBLMITGB2 | |
| SCHEMBL29185352 | 0.74 | HTR2A (0.37) | LMNAHTTMAPTBLMITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11793771-B2 | Immunomodulator compounds | CHEMOCENTRYX, INC. (US) | 2023-10-24 | — | — | US | disclosed |
| US-11793771-B2 | Immunomodulator compounds | CHEMOCENTRYX, INC. (US) | 2023-10-24 | — | — | US | disclosed |
| US-20180008554-A1 | IMMUNOMODULATOR COMPOUNDS | CHEMOCENTRYX, INC. | 2018-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11793771-B2 | Immunomodulator compounds | IL2, IL2RA, C3AR1 | LMNA 4728/4885HTT 4445/4885MAPT 4837/4885 |
| US-20180008554-A1 | IMMUNOMODULATOR COMPOUNDS | IL2, IL2RA, C3AR1 | LMNA 4704/4885HTT 4485/4885MAPT 4795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.