Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18483490 | 0.84 | PTGDR2 (0.55) | PTGDR2SLC2A1GAAGFER | |
| SCHEMBL16832433 | 0.82 | SLC2A1 (0.70) | PTGDR2SLC2A1GAAGFER | |
| SCHEMBL31673676 | 0.77 | POLB (0.70) | PTGDR2 | |
| SCHEMBL29050427 | 0.77 | ALDH1A1 (0.50) | PTGDR2SLC2A1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL16832937 | 0.76 | GAA (0.56) | PTGDR2ALDH1A1HTTSMN1; SMN2GAA | |
| SCHEMBL31466465 | 0.76 | PTGER1 (0.46) | PTGDR2ALDH1A1 | |
| SCHEMBL30063369 | 0.74 | PTGDR2 (0.47) | PTGDR2SLC2A1GAAGFER | |
| SCHEMBL29185672 | 0.73 | KDM4E (0.41) | PTGDR2ALDH1A1 | |
| SCHEMBL10173858 | 0.72 | PTGDR2 (0.81) | PTGDR2 | |
| SCHEMBL30128717 | 0.72 | LMNA (0.57) | PTGDR2HTTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4346805-A1 | PYRIMIDINE AND PYRIDINE AMINE COMPOUNDS AND USAGE THEREOF IN DISEASE TREATMENT | Epigen Biosciences, Inc. (US) | 2024-04-10 | — | — | EP | disclosed |
| CN-117500496-A | Pyrimidine and pyridinamine compounds and their use in the treatment of diseases | 艾匹根生物技术有限公司 | 2024-02-02 | — | — | CN | disclosed |
| WO-2022256075-A1 | PYRIMIDINE AND PYRIDINE AMINE COMPOUNDS AND USAGE THEREOF IN DISEASE TREATMENT | EPIGEN BIOSCIENCES, INC. (US) | 2022-12-08 | — | — | WO | disclosed |