SCHEMBL2918640

SCHEMBL2918640

CC/C(=C/c1ccccc1)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.63
CYP2C9 P11712 1/20 0.63
RECQL P46063 1/20 0.56
AKR1C3 P42330 1/20 0.55
TBXAS1 P24557 2/20 0.55
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
EPHX2 P34913 2/20 0.50
PPARG P37231 1/20 0.50
AKR1C1 Q04828 1/20 0.48
LMNA P02545 1/20 0.47
TDP1 Q9NUW8 1/20 0.46
HTT P42858 1/20 0.46
ALDH1A1 P00352 1/20 0.45
TSHR P16473 1/20 0.45
MME P08473 2/20 0.45
NR1I2 O75469 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL309762 1.00 CYP3A4 (0.63) CYP3A4CYP2C9RECQLAKR1C3TBXAS1
SCHEMBL57683 1.00 CYP3A4 (0.63) CYP3A4CYP2C9RECQLAKR1C3TBXAS1
SCHEMBL5173409 0.91 TBXAS1 (0.58) CYP3A4CYP2C9RECQLAKR1C3TBXAS1
Methacrylic Acid SCHEMBL10714804 0.91 CYP3A4 (0.54) CYP3A4CYP2C9RECQLAKR1C3TBXAS1
Oxirane SCHEMBL15646744 0.91 CYP3A4 (0.54) CYP3A4CYP2C9RECQLAKR1C3TBXAS1
SCHEMBL9061442 0.89 TP53 (0.59) CYP3A4CYP2C9RECQLAKR1C3TBXAS1
SCHEMBL15955486 0.88 CYP3A4 (0.55) CYP3A4CYP2C9RECQLAKR1C3TBXAS1
SCHEMBL15955485 0.88 CYP3A4 (0.55) CYP3A4CYP2C9RECQLAKR1C3TBXAS1
SCHEMBL5007835 0.88 CYP3A4 (0.51) CYP3A4CYP2C9RECQLAKR1C3TBXAS1
SCHEMBL30752458 0.86 RECQL (0.70) CYP3A4CYP2C9RECQLAKR1C3TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1747059-A1 PERVAPORATION COMPOSITE MEMBRANES McMaster University (CA) 2007-01-31 EP claimed
US-20060000778-A1 high-performance membrane designed for the selective removal of a polar fluid (water) from less polar fluids (organic solvents), by a pervaporation using a composite membrane contaiing ultrafiltration membrane as support ( e.g. cellulose acetate) and a crosslinked copolymer of anionic, cationic monomers MCMASTER UNIVERSITY (CA) 2006-01-05 US claimed
WO-2005102503-A1 PERVAPORATION COMPOSITE MEMBRANES MCMASTER UNIVERSITY (CA) 2005-11-03 WO claimed
JP-61136581-A None JP disclosed
EP-2226192-B1 DRYING SUBSTANCES, PREPARATION AND USE THEREOF ORIDION MEDICAL 1987 LTD (IL) 2016-08-31 EP disclosed
EP-2226116-B1 Drying tube, preparation and use thereof ORIDION MEDICAL 1987 LTD (IL) 2016-04-20 EP disclosed
US-20150283519-A1 DRYING SUBSTANCES, PREPARATION AND USE THEREOF ORIDION MEDICAL 1987 LTD. (IL) 2015-10-08 US disclosed
US-9090766-B2 Drying substances, preparation and use thereof ORIDION MEDICAL 1987 LTD. (IL) 2015-07-28 US disclosed
US-9067035-B2 Drying substances, preparation and use thereof ORIDION MEDICAL (1987) LTD. (IL) 2015-06-30 US disclosed
US-20140230652-A1 DRYING SUBSTANCES, PREPARATION AND USE THEREOF ORIDION MEDICAL (1987) LTD. (IL) 2014-08-21 US disclosed
US-8764888-B2 Drying substances, preparation and use thereof ORIDION MEDICAL 1987 LTD. (IL) 2014-07-01 US disclosed
US-7604746-B2 high-performance membrane designed for the selective removal of a polar fluid (water) from less polar fluids (organic solvents), by a pervaporation using a composite membrane contaiing ultrafiltration membrane as support ( e.g. cellulose acetate) and a crosslinked copolymer of anionic, cationic monomers MCMASTER UNIVERSITY (CA) 2009-10-20 US disclosed
US-20080171656-A1 Nanostructured metal-polyaniline composites ENERGY, U.S. DEPARTMENT OF 2008-07-17 US disclosed
US-20060000778-A1 high-performance membrane designed for the selective removal of a polar fluid (water) from less polar fluids (organic solvents), by a pervaporation using a composite membrane contaiing ultrafiltration membrane as support ( e.g. cellulose acetate) and a crosslinked copolymer of anionic, cationic monomers MCMASTER UNIVERSITY (CA) 2006-01-05 US disclosed
EP-0797459-B1 COATING PROCESS MEDICARB AB (SE) 2003-05-14 EP disclosed
US-5885647-A Coating process MEDICARB AB (SE) 1999-03-23 US disclosed
EP-0797459-A1 COATING PROCESS MEDICARB AB (SE) 1997-10-01 EP disclosed
WO-1996018423-A1 COATING PROCESS MEDICARB AB (SE) 1996-06-20 WO disclosed
EP-0482471-B1 Accepting element for thermo-sublimation print process AGFA GEVAERT AG (DE) 1995-06-28 EP disclosed
JP-S61136581-A METHOD OF MAKING RARE EARTH PHOSPHOR MOISTURE-RESISTANT MITSUBISHI CHEM IND LTD 1986-06-24 JP disclosed