SCHEMBL309762

SCHEMBL309762

CC/C(=C\c1ccccc1)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.63
CYP2C9 P11712 1/20 0.63
RECQL P46063 1/20 0.56
AKR1C3 P42330 1/20 0.55
TBXAS1 P24557 2/20 0.55
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
EPHX2 P34913 2/20 0.50
PPARG P37231 1/20 0.50
AKR1C1 Q04828 1/20 0.48
LMNA P02545 1/20 0.47
TDP1 Q9NUW8 1/20 0.46
HTT P42858 1/20 0.46
ALDH1A1 P00352 1/20 0.45
TSHR P16473 1/20 0.45
MME P08473 2/20 0.45
NR1I2 O75469 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2918640 1.00 CYP3A4 (0.63) CYP3A4CYP2C9RECQLAKR1C3TBXAS1
SCHEMBL57683 1.00 CYP3A4 (0.63) CYP3A4CYP2C9RECQLAKR1C3TBXAS1
SCHEMBL5173409 0.91 TBXAS1 (0.58) CYP3A4CYP2C9RECQLAKR1C3TBXAS1
Methacrylic Acid SCHEMBL10714804 0.91 CYP3A4 (0.54) CYP3A4CYP2C9RECQLAKR1C3TBXAS1
Oxirane SCHEMBL15646744 0.91 CYP3A4 (0.54) CYP3A4CYP2C9RECQLAKR1C3TBXAS1
SCHEMBL9061442 0.89 TP53 (0.59) CYP3A4CYP2C9RECQLAKR1C3TBXAS1
SCHEMBL15955486 0.88 CYP3A4 (0.55) CYP3A4CYP2C9RECQLAKR1C3TBXAS1
SCHEMBL15955485 0.88 CYP3A4 (0.55) CYP3A4CYP2C9RECQLAKR1C3TBXAS1
SCHEMBL5007835 0.88 CYP3A4 (0.51) CYP3A4CYP2C9RECQLAKR1C3TBXAS1
SCHEMBL30752458 0.86 RECQL (0.70) CYP3A4CYP2C9RECQLAKR1C3TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3548890-B1 MEANS AND METHODS FOR VISUALIZATION OF TISSUE STRUCTURES GRETZ NORBERT (DE) 2024-03-27 EP claimed
EP-3548890-A1 MEANS AND METHODS FOR VISUALIZATION OF TISSUE STRUCTURES Gretz, Norbert (DE) 2019-10-09 EP claimed
WO-2018100089-A1 MEANS AND METHODS FOR VISUALIZATION OF TISSUE STRUCTURES GRETZ NORBERT (DE) 2018-06-07 WO claimed
EP-2328938-B1 RADICALLY FUNCTIONALIZED OLEFIN-BASED POLYMER WITH REDUCED MOLECULAR WEIGHT CHANGE AND METHOD DOW GLOBAL TECHNOLOGIES LLC (US) 2015-04-01 EP claimed
US-5961875-A Antifreeze/coolant composition containing cinnamic acid CCI CO., LTD. (JP) 1999-10-05 US claimed
US-5876492-A Ink compositions containing esters XEROX CORPORATION (US) 1999-03-02 US claimed
EP-3548890-B1 MEANS AND METHODS FOR VISUALIZATION OF TISSUE STRUCTURES GRETZ NORBERT (DE) 2024-03-27 EP disclosed
US-20230092002-A1 MEANS AND METHODS FOR VISUALIZATION OF TISSUE STRUCTURES GRETZ NORBERT (DE) 2023-03-23 US disclosed
CN-112745210-B Method for preparing alpha, beta-unsaturated carboxylic acid compound 中国科学院大连化学物理研究所 2022-02-15 CN disclosed
CN-108026028-B Treatment of diabetes and metabolic syndrome with novel dual modulators of soluble epoxide hydrolase and peroxisome proliferator-activated receptors 威斯康星州医药大学股份有限公司 2021-11-09 CN disclosed
EP-2145042-B2 TEXTILE SCENTING HENKEL AG & CO KGAA (DE) 2021-10-06 EP disclosed
CN-112745210-A Method for preparing alpha, beta-unsaturated carboxylic acid compound 中国科学院大连化学物理研究所 2021-05-04 CN disclosed
US-20190353565-A1 MEANS AND METHODS FOR VISUALIZATION OF TISSUE STRUCTURES GRETZ NORBERT (DE) 2019-11-21 US disclosed
US-5547967-A HYPOTENSIVE AGENT, ANTIISCHEMIC AGENT KALI-CHEMIE PHARMA GMBH (DE) 1996-08-20 US disclosed
EP-0048433-B1 NOVEL AMIDINE COMPOUNDS, PROCESS FOR PRODUCING SAME AND ANTI-COMPLEMENT AGENT COMPRISING THEM TORII & CO., LTD. (JP) 1986-05-28 EP disclosed
US-4532255-A Amidine compounds and anticomplement agent comprising same TORII & CO., LTD. (JP) 1985-07-30 US disclosed
US-4454338-A 6-AMIDINO-2-NATHTHYL-4-GUANIDINOBENZOATE TORII & CO., LTD. (JP) 1984-06-12 US disclosed
EP-0048433-A2 Novel amidine compounds, process for producing same and anti-complement agent comprising them TORII & CO., LTD. (JP) 1982-03-31 EP disclosed
US-4166131-A ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANTIARTHRITIC AGENT HEXACHIMIE SOCIETE ANONYME (FR) 1979-08-28 US disclosed
US-4010191-A Acyl derivatives of substituted bis-arylalkylamino compounds DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1977-03-01 US disclosed