Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27845876 | 0.81 | ALDH1A1 (0.38) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1079189 | 0.73 | DYRK1A (0.32) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL29187008 | 0.73 | GBA1 (0.38) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL25401107 | 0.72 | — | — | |
| SCHEMBL3466128 | 0.69 | ALDH1A1 (0.43) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL17207701 | 0.69 | — | — | |
| SCHEMBL5170675 | 0.69 | — | — | |
| SCHEMBL30620625 | 0.69 | — | — | |
| SCHEMBL1094456 | 0.69 | — | — | |
| SCHEMBL30067859 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813302-A | Substituted tetrahydrofuran-2-carboxamides as sodium channel modulators | 沃泰克斯药物股份有限公司 | 2024-04-02 | — | — | CN | disclosed |