⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1094456 | 1.00 | — | — | |
| SCHEMBL22289303 | 0.79 | ADRA2A (0.39) | — | |
| SCHEMBL6783268 | 0.79 | ALDH1A1 (0.44) | — | |
| SCHEMBL27863825 | 0.78 | ERN1 (0.39) | — | |
| SCHEMBL25401107 | 0.77 | — | — | |
| SCHEMBL17207701 | 0.77 | — | — | |
| SCHEMBL30620625 | 0.77 | — | — | |
| SCHEMBL5170675 | 0.77 | — | — | |
| SCHEMBL7609085 | 0.76 | ERN1 (0.38) | — | |
| SCHEMBL986987 | 0.74 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119039275-A | Preparation method of biologically active imidazole derivative 2,3, 5-tripyridine substituted imidazole | 武汉理工大学深圳研究院 | 2024-11-29 | — | — | CN | claimed |
| EP-4737455-A1 | COMPOUND CONTAINING MULTI-FUSED RING STRUCTURE | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2026-05-06 | — | — | EP | disclosed |
| US-20260098037-A1 | COMPOUND CONTAINING MULTI-FUSED RING STRUCTURE | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2026-04-09 | — | — | US | disclosed |
| WO-2025215558-A1 | COMPOUNDS FOR SPLICING MODULATION | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2025-10-16 | — | — | WO | disclosed |
| US-20250215017-A1 | TGF-ß INHIBITOR COMPOUND AND USE THEROF | MEDINNO PHARMACEUTICAL TECHNOLOGY (ZHUHAI) CO., LTD. (CN) | 2025-07-03 | — | — | US | disclosed |
| US-20250179094-A1 | TGF-B INHIBITOR COMPOUND AND USE THEREOF | MEDINNO PHARMACEUTICAL TECHNOLOGY (ZHUHAI) CO., LTD. (CN) | 2025-06-05 | — | — | US | disclosed |
| US-20250179036-A1 | MORPHOLINE-3-CARBOXAMIDE DERIVATIVES AS PROSTAGLANDIN E2 RECEPTOR 4 (EP4) AGONISTS FOR THE TREATMENT OF GASTROINTESTINAL AND PULMONARY DISEASES | NXERA PHARMA UK LIMITED (GB) | 2025-06-05 | — | — | US | disclosed |
| CN-120077044-A | Compounds containing multiple condensed ring structures | 正大天晴药业集团股份有限公司 | 2025-05-30 | — | — | CN | disclosed |
| EP-4556477-A1 | TGF-BETA INHIBITOR COMPOUND AND USE THEREOF | Medinno Pharmaceutical Technology (Zhuhai) Co., Ltd. (CN) | 2025-05-21 | — | — | EP | disclosed |
| EP-4556478-A1 | TGF-BETA INHIBITOR COMPOUND AND USE THEREOF | Medinno Pharmaceutical Technology (Zhuhai) Co., Ltd. (CN) | 2025-05-21 | — | — | EP | disclosed |
| WO-2025085560-A1 | LYSINE ACETYLTRANSFERASE INHIBITORS | Kronos Bio, Inc. (US) | 2025-04-24 | — | — | WO | disclosed |
| WO-2025085564-A1 | LYSINE ACETYLTRANSFERASE INHIBITORS | Kronos Bio, Inc. (US) | 2025-04-24 | — | — | WO | disclosed |
| WO-2025064829-A1 | A MOLECULAR SCAFFOLD FOR DEPLETING HRPN13 AND A SELECT GROUP OF KEN BOX PROTEINS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2025-03-27 | — | — | WO | disclosed |
| WO-2025002326-A1 | COMPOUND CONTAINING MULTI-FUSED RING STRUCTURE | 正大天晴药业集团股份有限公司 | 2025-01-02 | — | — | WO | disclosed |
| CN-119039275-A | Preparation method of biologically active imidazole derivative 2,3, 5-tripyridine substituted imidazole | 武汉理工大学深圳研究院 | 2024-11-29 | — | — | CN | disclosed |
| EP-4387609-A2 | ARYL SULFONYL (HYDROXY) PIPERIDINES AS CCR6 INHIBITORS | ChemoCentryx, Inc. (US) | 2024-06-26 | — | — | EP | disclosed |
| WO-2024046253-A1 | SODIUM CHANNEL REGULATOR AND USE THEREOF | 上海汇伦医药股份有限公司 | 2024-03-07 | — | — | WO | disclosed |
| WO-2023023532-A2 | ARYL SULFONYL (HYDROXY) PIPERIDINES AS CCR6 INHIBITORS | CHEMOCENTRYX, INC. (US) | 2023-02-23 | — | — | WO | disclosed |
| WO-2022233302-A1 | PYRIMIDINONE DERIVATIVE AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND USE | 上海赛默罗生物科技有限公司 | 2022-11-10 | — | — | WO | disclosed |