Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.41 |
| ▸ | ADH1B | P00325 | 1/20 | 0.41 |
| ▸ | ADH1C | P00326 | 1/20 | 0.41 |
| ▸ | ADH1A | P07327 | 1/20 | 0.41 |
| ▸ | ADH4 | P08319 | 1/20 | 0.41 |
| ▸ | ADH7 | P40394 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.36 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615995 | 0.86 | CYP2C19 (0.43) | TSHRALDH1A1CYP1A2CYP2C19PAOX | |
| SCHEMBL29243939 | 0.84 | TSHR (0.48) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| Bromide SCHEMBL126229 | 0.81 | TSHR (0.87) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| Bromide SCHEMBL4456628 | 0.81 | TSHR (0.87) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| Bromide SCHEMBL7093599 | 0.81 | TSHR (0.87) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| Bromide SCHEMBL6390459 | 0.81 | TSHR (0.87) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| Bromide SCHEMBL6395851 | 0.81 | TSHR (0.87) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| Bromide SCHEMBL128597 | 0.81 | TSHR (0.87) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| Bromide SCHEMBL29136406 | 0.81 | TSHR (0.87) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| Bromide SCHEMBL28708092 | 0.81 | TSHR (0.87) | TSHRALDH1A1S1PR2S1PR4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114806603-B | Novel Si-C organosilicon quaternary ammonium salt surfactant and preparation method thereof | 滁州学院 | 2023-06-09 | — | — | CN | disclosed |