Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.87 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.87 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.58 |
| ▸ | ADH1B | P00325 | 1/20 | 0.57 |
| ▸ | ADH1C | P00326 | 1/20 | 0.57 |
| ▸ | ADH1A | P07327 | 1/20 | 0.57 |
| ▸ | ADH4 | P08319 | 1/20 | 0.57 |
| ▸ | ADH7 | P40394 | 1/20 | 0.57 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.56 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.56 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6385119 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| Bromide SCHEMBL29136407 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| Bromide SCHEMBL29136406 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| Bromide SCHEMBL28708092 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| Bromide SCHEMBL128597 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| Bromide SCHEMBL6395851 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| Bromide SCHEMBL6390459 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| Bromide SCHEMBL7093599 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| Bromide SCHEMBL4456628 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C | |
| Bromide SCHEMBL27860834 | 1.00 | TSHR (0.87) | TSHRALDH1A1EPHX1ADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 495 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115584092-A | Transformer sealing fluororubber composition and preparation method thereof | 上海道氟实业有限公司 | 2023-01-10 | — | — | CN | claimed |
| US-6283336-B1 | Article for the delivery of foam products | THE PROCTER & GAMBLE COMPANY | 2001-09-04 | — | — | US | claimed |
| WO-2001021501-A1 | ARTICLE FOR THE DELIVERY OF FOAM PRODUCTS | THE PROCTER & GAMBLE COMPANY (US) | 2001-03-29 | — | — | WO | claimed |
| US-20260096558-A1 | THE USE OF PHYTIC ACID CHELATOR FOR MICROBIAL RAPID KILL | HENKEL AG & CO KGAA (DE) | 2026-04-09 | — | — | US | disclosed |
| US-20240360391-A1 | NONWOVEN WIPES, CLEANING COMPOSITIONS, AND ASSOCIATED PACKAGING | DERMAL BIOMICS INC (US) | 2024-10-31 | — | — | US | disclosed |
| EP-2367852-B1 | COSMETIC COMPOSITION CONTAINING ACETYLATED OLIGOGLUCURONANS | SEDERMA SA (FR) | 2023-08-30 | — | — | EP | disclosed |
| CN-115584092-B | Transformer sealing fluororubber composition and preparation method thereof | 上海道氟实业有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-115988962-A | Graftable biocidal linkers and polymers and uses thereof | 德保吉分子公司 | 2023-04-18 | — | — | CN | disclosed |
| EP-3744729-B1 | PEPTIDES, COMPOSITIONS COMPRISING THEM AND COSMETIC AND DERMOPHARMACEUTICAL USES | SEDERMA SA (FR) | 2023-03-01 | — | — | EP | disclosed |
| CN-115584092-A | Transformer sealing fluororubber composition and preparation method thereof | 上海道氟实业有限公司 | 2023-01-10 | — | — | CN | disclosed |
| US-11331305-B2 | Peptides for skin rejuvenation and methods of using the same | ANTEIS SA (CH) | 2022-05-17 | — | — | US | disclosed |
| WO-1996032092-A2 | CLEANSING EMULSIONS | THE PROCTER & GAMBLE COMPANY (US) | 1996-10-17 | — | — | WO | disclosed |
| US-5534265-A | INSOLUBILE POLYMER PARTICLES, GELLING AGENT, SURFACTANT, EMOLIENT | THE PROCTER & GAMBLE COMPANY (US) | 1996-07-09 | — | — | US | disclosed |
| EP-0714283-A1 | PERSONAL CLEANSING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1996-06-05 | — | — | EP | disclosed |
| WO-1996006596-A1 | THICKENED NONABRASIVE PERSONAL CLEANSING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1996-03-07 | — | — | WO | disclosed |
| WO-1996006595-A1 | PERSONAL CLEANSING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1996-03-07 | — | — | WO | disclosed |
| EP-0693920-A1 | COMPOSITIONS FOR IMPARTING AN ARTIFICIAL TAN AND PROTECTING THE SKIN FROM UV RADIATION | THE PROCTER & GAMBLE COMPANY (US) | 1996-01-31 | — | — | EP | disclosed |
| WO-1995024179-A1 | LOW pH, HYDROLYTICALLY STABLE, COSMETIC COMPOSITIONS CONTAINING ACIDIC ACTIVES | THE PROCTER & GAMBLE COMPANY (US) | 1995-09-14 | — | — | WO | disclosed |
| WO-1995003781-A1 | PERSONAL CLEANSING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1995-02-09 | — | — | WO | disclosed |
| WO-1994023693-A1 | COMPOSITIONS FOR IMPARTING AN ARTIFICIAL TAN AND PROTECTING THE SKIN FROM UV RADIATION | THE PROCTER & GAMBLE COMPANY (US) | 1994-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260096558-A1 | THE USE OF PHYTIC ACID CHELATOR FOR MICROBIAL RAPID KILL | CUTA, TRAFD1, POLR1C | SIGMAR1 1196/4885TSHR 1872/4885ALDH1A1 2504/4885 |
| US-11331305-B2 | Peptides for skin rejuvenation and methods of using the same | CUTA, PLOD3, MMP13 | SIGMAR1 4817/4885TSHR 3828/4885ALDH1A1 3368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.