Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 5/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14929532 | 0.83 | KMT2A (0.59) | KMT2AL3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL29216412 | 0.82 | PDPK1 (0.42) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL29188504 | 0.81 | KMT2A (0.41) | KMT2AL3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL11685920 | 0.80 | KMT2A (0.56) | KMT2AL3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL28268761 | 0.76 | KMT2A (0.60) | KMT2AL3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL31333105 | 0.75 | KMT2A (0.50) | KMT2AL3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL31333100 | 0.75 | KMT2A (0.50) | KMT2AL3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL11687690 | 0.75 | KMT2A (0.50) | KMT2AL3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL28148149 | 0.74 | KMT2A (0.62) | KMT2AL3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL23791207 | 0.72 | KMT2A (0.60) | KMT2AL3MBTL1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117865869-A | Method for synthesizing 1-trifluoromethyl indole compound by taking 2-alkynyl aromatic amine as raw material | 江南大学 | 2024-04-12 | — | — | CN | disclosed |
| CN-117865870-A | Method for synthesizing 1-trifluoromethyl indole compound by taking 2-alkynyl aryl isothiocyanate as raw material | 江南大学 | 2024-04-12 | — | — | CN | disclosed |