Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 4/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11685920 | 0.86 | KMT2A (0.56) | KMT2AL3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL29188490 | 0.83 | KMT2A (0.56) | KMT2AL3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL11687690 | 0.80 | KMT2A (0.50) | KMT2AL3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL17549549 | 0.78 | KMT2A (0.40) | KMT2AL3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL11837914 | 0.77 | L3MBTL1 (0.58) | KMT2AL3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL11688825 | 0.77 | ALDH1A1 (0.51) | KMT2AL3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL18014720 | 0.75 | ALDH1A1 (0.60) | KMT2AL3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL11433591 | 0.75 | ALDH1A1 (0.60) | KMT2AL3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL7756916 | 0.75 | KDM4E (0.42) | KMT2AALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL214075 | 0.75 | KMT2A (1.00) | KMT2AL3MBTL1ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113683551-B | N-tert-butyl-2-phenylindole derivative, preparation method and application | 常州大学 | 2023-09-26 | — | — | CN | claimed |
| CN-113683551-A | N-tert-butyl-2-phenylindole derivative, preparation method and application | 常州大学 | 2021-11-23 | — | — | CN | claimed |
| CN-113683551-B | N-tert-butyl-2-phenylindole derivative, preparation method and application | 常州大学 | 2023-09-26 | — | — | CN | disclosed |
| CN-113683551-B | N-tert-butyl-2-phenylindole derivative, preparation method and application | 常州大学 | 2023-09-26 | — | — | CN | disclosed |
| CN-113683551-B | N-tert-butyl-2-phenylindole derivative, preparation method and application | 常州大学 | 2023-09-26 | — | — | CN | disclosed |
| CN-113683551-A | N-tert-butyl-2-phenylindole derivative, preparation method and application | 常州大学 | 2021-11-23 | — | — | CN | disclosed |
| CN-113683551-A | N-tert-butyl-2-phenylindole derivative, preparation method and application | 常州大学 | 2021-11-23 | — | — | CN | disclosed |
| CN-113683551-A | N-tert-butyl-2-phenylindole derivative, preparation method and application | 常州大学 | 2021-11-23 | — | — | CN | disclosed |
| US-9409938-B2 | Tungsten oxo alkylidene complexes for Zselective olefin metathesis | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-08-09 | — | — | US | disclosed |
| US-20160009746-A1 | TUNGSTEN OXO ALKYLIDENE COMPLEXES FOR Z SELECTIVE OLEFIN METATHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2016-01-14 | — | — | US | disclosed |
| US-9085595-B2 | Tungsten oxo alkylidene complexes for Z selective olefin metathesis | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-07-21 | — | — | US | disclosed |
| WO-2013159229-A1 | SILANYLOXYARYL PHOSPHINE LIGAND AND USES THEREOF IN C-N CROSS-COUPLING | DALHOUSIE UNIVERSITY (CA) | 2013-10-31 | — | — | WO | disclosed |
| WO-2013159229-A1 | SILANYLOXYARYL PHOSPHINE LIGAND AND USES THEREOF IN C-N CROSS-COUPLING | DALHOUSIE UNIVERSITY (CA) | 2013-10-31 | — | — | WO | disclosed |
| US-20130116434-A1 | TUNGSTEN OXO ALKYLIDENE COMPLEXES FOR Z SELECTIVE OLEFIN METATHESIS | TRUSTEES OF BOSTON COLLEGE (US) | 2013-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116434-A1 | TUNGSTEN OXO ALKYLIDENE COMPLEXES FOR Z SELECTIVE OLEFIN METATHESIS | SOD1, ZRANB2, ZCCHC8 | KMT2A 2188/4885L3MBTL1 544/4885ALDH1A1 2922/4885 |
| US-20160009746-A1 | TUNGSTEN OXO ALKYLIDENE COMPLEXES FOR Z SELECTIVE OLEFIN METATHESIS | SOD1, ZRANB2, ZCCHC8 | KMT2A 2188/4885L3MBTL1 544/4885ALDH1A1 2922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.