SCHEMBL29188742

SCHEMBL29188742

CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(Cl)s2)CC1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.61
HPGD P15428 1/20 0.61
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
MAPT P10636 5/20 0.56
POLB P06746 2/20 0.53
CA12 O43570 1/20 0.51
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
CA7 P43166 1/20 0.51
CA9 Q16790 1/20 0.51
HTT P42858 2/20 0.47
LMNA P02545 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
YEATS4 O95619 1/20 0.47
STS P08842 1/20 0.46
GPR119 Q8TDV5 2/20 0.45
CYP2C9 P11712 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL226425 0.82 STS (0.54) ALDH1A1HPGDKMT2AMAPTHTT
SCHEMBL25003025 0.81 MEN1 (0.50) ALDH1A1MEN1KMT2AMAPTPOLB
SCHEMBL27166080 0.78 MEN1 (0.40) ALDH1A1HPGDMEN1KMT2APOLB
SCHEMBL20615620 0.76 KDM4E (0.64) MEN1KMT2AMAPTLMNACYP2C9
SCHEMBL3159336 0.76 GAA (0.60) ALDH1A1KMT2AMAPTHTTLMNA
SCHEMBL20460413 0.76 HPGD (0.96) ALDH1A1HPGDMAPTPOLBCA12
SCHEMBL1256025 0.75 KMT2A (0.92) ALDH1A1HPGDMEN1KMT2AMAPT
SCHEMBL20601090 0.75 ALDH1A1 (0.45) ALDH1A1KMT2AMAPTHTTSMN1; SMN2
SCHEMBL22022722 0.75 ALDH1A1 (0.45) ALDH1A1KMT2AMAPTHTTSMN1; SMN2
SCHEMBL20615702 0.75 SMN1; SMN2 (0.50) ALDH1A1KMT2AMAPTHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117820287-A Magnolol derivative, and preparation method and application thereof 中国药科大学 2024-04-05 CN disclosed