Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11293119 | 0.83 | GAA (0.85) | GAAALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL226265 | 0.82 | ALDH1A1 (0.54) | GAAALDH1A1SMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL26673548 | 0.81 | HSD17B10 (0.55) | GAALMNASMN1; SMN2ALOX15TSHR | |
| SCHEMBL24710943 | 0.81 | GAA (0.66) | GAAALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL14227532 | 0.81 | GAA (0.66) | GAAALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL2274835 | 0.80 | GBA1 (0.55) | ALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL10280045 | 0.80 | GAA (0.74) | GAAALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL26673578 | 0.80 | LMNA (0.53) | GAAALDH1A1LMNASMN1; SMN2ALOX15 | |
| SCHEMBL12184245 | 0.79 | GAA (0.72) | GAAALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL12706353 | 0.78 | GAA (0.66) | GAAALDH1A1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820287-B | Magnolol derivative, and preparation method and application thereof | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-117800942-B | Thiophene piperazine amide derivative, composition and application thereof | 徐州医科大学 | 2025-04-25 | — | — | CN | disclosed |
| US-20250092067-A1 | APT1 and APT2 Inhibitors and Uses Thereof | CORNELL UNIVERSITY | 2025-03-20 | — | — | US | disclosed |
| CN-117820287-A | Magnolol derivative, and preparation method and application thereof | 中国药科大学 | 2024-04-05 | — | — | CN | disclosed |
| CN-117800942-A | Thiophene piperazine amide derivative, composition and application thereof | 徐州医科大学 | 2024-04-02 | — | — | CN | disclosed |
| WO-2022246115-A1 | APT1 AND APT2 INHIBITORS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2022-11-24 | — | — | WO | disclosed |
| EP-1697354-B1 | ISOTHIAZOLE DIOXIDES AS CXC- AND CC- CHEMOKINE RECEPTOR LIGANDS | MERCK SHARP & DOHME (US) | 2013-08-07 | — | — | EP | disclosed |
| EP-2310395-B1 | 9-SUBSTITUTED-B-CARBOXY-OXADIAZINO-QUINOLONE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS ANTI-BACTERIALS | VETOQUINOL SA (FR) | 2012-01-18 | — | — | EP | disclosed |
| US-8071590-B2 | 9-substituted-5-carboxy-oxadiazino-quinolone derivatives, their preparation and their application as anti-bacterials | VETOQUINOL SA (FR) | 2011-12-06 | — | — | US | disclosed |
| US-8071590-B2 | 9-substituted-5-carboxy-oxadiazino-quinolone derivatives, their preparation and their application as anti-bacterials | VETOQUINOL SA (FR) | 2011-12-06 | — | — | US | disclosed |
| US-20060094727-A1 | INHIBITORS OF MACROPHASE MIGRATION INHIBITORY FACTOR AND METHODS FOR IDENTIFYING THE SAME | AVANIR PHARMACEUTICALS | 2006-05-04 | — | — | US | disclosed |
| CN-1750823-A | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | AVANIR PHARMACEUTICALS (US) | 2006-03-22 | — | — | CN | disclosed |
| US-20050287617-A1 | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | AVANIR PHARMACEUTICALS | 2005-12-29 | — | — | US | disclosed |
| US-20050282236-A1 | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | AVANIR PHARMACEUTICALS | 2005-12-22 | — | — | US | disclosed |
| EP-1594501-A2 | INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR AND METHODS FOR IDENTIFYING THE SAME | Avanir Pharmaceuticals (US) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004074218-A2 | INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR AND METHODS FOR IDENTIFYING THE SAME | AVANIR PHARMACEUTICALS (US) | 2004-09-02 | — | — | WO | disclosed |
| CN-1523989-A | Macrophage migration inhibitory factor inhibitor and identification method thereof | ������˹ҩƷ��˾ | 2004-08-25 | — | — | CN | disclosed |
| EP-1389110-A2 | INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR AND METHODS FOR IDENTIFYING THE SAME | Avanir Pharmaceuticals (US) | 2004-02-18 | — | — | EP | disclosed |
| US-20030195194-A1 | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | AVANIR PHARMACEUTICALS | 2003-10-16 | — | — | US | disclosed |
| WO-2002094203-A2 | INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR AND METHODS FOR IDENTIFYING THE SAME | AVANIR PHARMACEUTICALS (US) | 2002-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094727-A1 | INHIBITORS OF MACROPHASE MIGRATION INHIBITORY FACTOR AND METHODS FOR IDENTIFYING THE SAME | MIF, MSR1, MMP12 | GAA 811/4885ALDH1A1 1637/4885LMNA 2556/4885 |
| US-20250092067-A1 | APT1 and APT2 Inhibitors and Uses Thereof | LYPLA2, LYPLA1, PPT1 | GAA 2549/4885ALDH1A1 3083/4885LMNA 3992/4885 |
| US-20030195194-A1 | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | MIF, MSR1, MMP12 | GAA 1645/4885ALDH1A1 1863/4885LMNA 2561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.