Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.31 |
| ▸ | CETP | P11597 | 1/20 | 0.31 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.30 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.30 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29189950 | 0.91 | CHRNA7 (0.39) | CHRNA7KCNH2S1PR1S1PR3 | |
| SCHEMBL29189969 | 0.86 | S1PR1 (0.32) | CHRNA7KCNH2S1PR1S1PR3CETP | |
| SCHEMBL29189988 | 0.86 | S1PR1 (0.32) | CHRNA7KCNH2S1PR1S1PR3CETP | |
| SCHEMBL24818822 | 0.84 | VSIR (0.34) | CETP | |
| SCHEMBL30152901 | 0.84 | VSIR (0.34) | CETP | |
| SCHEMBL29190151 | 0.81 | S1PR1 (0.34) | S1PR1S1PR3CETP | |
| SCHEMBL29190103 | 0.80 | S1PR1 (0.33) | S1PR1S1PR3CETP | |
| SCHEMBL29190063 | 0.79 | VSIR (0.38) | S1PR1S1PR3 | |
| SCHEMBL29189945 | 0.79 | VSIR (0.38) | S1PR1S1PR3 | |
| SCHEMBL29189996 | 0.79 | VSIR (0.37) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |