Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 9/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.35 |
| ▸ | ACP1 | P24666 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29189924 | 0.91 | CHRNA7 (0.31) | CHRNA7KCNH2S1PR1S1PR3 | |
| SCHEMBL29189988 | 0.89 | S1PR1 (0.32) | CHRNA7KCNH2S1PR1S1PR3ACP1 | |
| SCHEMBL29189969 | 0.89 | S1PR1 (0.32) | CHRNA7KCNH2S1PR1S1PR3ACP1 | |
| SCHEMBL24820425 | 0.83 | VSIR (0.34) | CHRNA7KCNH2S1PR1S1PR3CYP1A2 | |
| SCHEMBL30152666 | 0.83 | VSIR (0.34) | CHRNA7KCNH2S1PR1S1PR3CYP1A2 | |
| SCHEMBL29190151 | 0.82 | S1PR1 (0.34) | S1PR1S1PR3 | |
| SCHEMBL29189965 | 0.82 | S1PR1 (0.33) | S1PR1S1PR3 | |
| SCHEMBL29189963 | 0.82 | S1PR1 (0.33) | S1PR1S1PR3 | |
| SCHEMBL29190041 | 0.82 | S1PR1 (0.33) | S1PR1S1PR3 | |
| SCHEMBL29190103 | 0.81 | S1PR1 (0.33) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |