Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 12/20 | 0.35 |
| ▸ | CETP | P11597 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.30 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29190020 | 1.00 | CBLB (0.35) | CBLBCETPHSD11B1ADORA2AHSD17B1 | |
| SCHEMBL29190046 | 0.87 | HSD11B1 (0.33) | CBLBCETPHSD11B1HSD17B1HSD11B2 | |
| SCHEMBL29190043 | 0.87 | HSD11B1 (0.33) | CBLBCETPHSD11B1HSD17B1HSD11B2 | |
| SCHEMBL29190161 | 0.86 | MAPK1 (0.34) | CBLBCETPLRRK2 | |
| SCHEMBL29189960 | 0.86 | CBLB (0.32) | CBLBCETP | |
| SCHEMBL29190083 | 0.86 | CBLB (0.32) | CBLBCETP | |
| SCHEMBL29190159 | 0.86 | MAPK1 (0.34) | CBLBCETPLRRK2 | |
| SCHEMBL29189958 | 0.86 | CBLB (0.32) | CBLBCETP | |
| SCHEMBL24820265 | 0.85 | VSIR (0.35) | CBLBCETP | |
| SCHEMBL24820264 | 0.85 | VSIR (0.35) | CBLBCETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |