Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 4/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152913 | 1.00 | CBLB (0.36) | CBLBPIK3R1MAPK13MAPK12MAPK11 | |
| SCHEMBL30153115 | 0.92 | CBLB (0.40) | CBLBPIK3R1P2RX7HSD11B1 | |
| SCHEMBL29189897 | 0.92 | CBLB (0.40) | CBLBPIK3R1P2RX7HSD11B1 | |
| SCHEMBL29190107 | 0.88 | CBLB (0.31) | CBLB | |
| SCHEMBL30152945 | 0.88 | CBLB (0.31) | CBLB | |
| SCHEMBL24819939 | 0.86 | CBLB (0.45) | CBLBPIK3R1 | |
| SCHEMBL30153218 | 0.86 | CETP (0.32) | CBLB | |
| SCHEMBL24819899 | 0.83 | CBLB (0.39) | CBLBP2RX7HSD11B1VSIR | |
| SCHEMBL30963807 | 0.79 | CBLB (0.32) | CBLB | |
| SCHEMBL30963780 | 0.78 | CBLB (0.32) | CBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |