Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 16/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30153213 | 0.92 | CBLB (0.37) | CBLB | |
| SCHEMBL30153117 | 0.89 | CBLB (0.47) | CBLBPTGES | |
| SCHEMBL24819935 | 0.89 | CBLB (0.47) | CBLBPTGES | |
| SCHEMBL30153246 | 0.85 | CBLB (0.37) | CBLB | |
| SCHEMBL29190056 | 0.85 | CBLB (0.37) | CBLB | |
| SCHEMBL24818718 | 0.80 | CBLB (0.47) | CBLBPTGES | |
| SCHEMBL30153147 | 0.80 | CBLB (0.32) | CBLB | |
| SCHEMBL29190062 | 0.79 | MAP3K5 (0.37) | CBLB | |
| SCHEMBL30792030 | 0.79 | MAP3K5 (0.37) | CBLB | |
| SCHEMBL30792214 | 0.78 | MAP3K5 (0.36) | CBLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359381-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |