Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29190070 | 0.86 | CBLB (0.42) | CBLBHSD11B1S1PR1S1PR3SCN9A | |
| SCHEMBL29190075 | 0.85 | HSD11B1 (0.42) | CBLBHSD11B1HCAR1 | |
| SCHEMBL29190036 | 0.78 | CBLB (0.36) | CBLBHSD11B1S1PR1S1PR3HDAC11 | |
| SCHEMBL29190004 | 0.77 | DPP4 (0.35) | CBLBHSD11B1HCAR1 | |
| SCHEMBL29190081 | 0.74 | CBLB (0.38) | CBLBLMNAHSD11B1S1PR1S1PR3 | |
| SCHEMBL24820285 | 0.72 | SCN9A (0.38) | CBLBALDH1A1HPGDHSD11B1HDAC11 | |
| SCHEMBL30153353 | 0.72 | SCN9A (0.38) | CBLBS1PR1S1PR3SCN9A | |
| SCHEMBL30152588 | 0.72 | SCN9A (0.38) | CBLBALDH1A1HPGDHSD11B1HDAC11 | |
| SCHEMBL24818728 | 0.72 | SCN9A (0.38) | CBLBS1PR1S1PR3SCN9A | |
| SCHEMBL29189967 | 0.72 | KMT2A (0.37) | CBLBHSD11B1S1PR1S1PR3SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |