Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 4/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | C1R | P00736 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30153353 | 0.90 | SCN9A (0.38) | CBLBCETPSCN9AS1PR1S1PR3 | |
| SCHEMBL24818728 | 0.90 | SCN9A (0.38) | CBLBCETPSCN9AS1PR1S1PR3 | |
| SCHEMBL29190150 | 0.85 | C1R (0.42) | CBLBC1RMETHSD11B1 | |
| SCHEMBL29190059 | 0.85 | CETP (0.37) | CBLBCETPS1PR1CLK1SMN1; SMN2 | |
| SCHEMBL24818726 | 0.82 | HPGD (0.37) | CBLBCETPSCN9ARARBS1PR1 | |
| SCHEMBL30152816 | 0.82 | HPGD (0.37) | CBLBCETPSCN9ARARBS1PR1 | |
| SCHEMBL24819809 | 0.81 | CETP (0.38) | CBLBCETPSCN9AS1PR1S1PR3 | |
| SCHEMBL30153136 | 0.81 | CETP (0.38) | CBLBCETPSCN9AS1PR1S1PR3 | |
| SCHEMBL29190072 | 0.78 | CBLB (0.36) | CBLBSCN9AFABP4S1PR1S1PR3 | |
| SCHEMBL29190151 | 0.77 | S1PR1 (0.34) | CBLBCETPS1PR1S1PR3HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |