Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 16/20 | 0.57 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.54 |
| ▸ | FLT3 | P36888 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
| ▸ | JAK1 | P23458 | 2/20 | 0.49 |
| ▸ | BRD2 | P25440 | 2/20 | 0.49 |
| ▸ | JAK3 | P52333 | 2/20 | 0.49 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.49 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | ROS1 | P08922 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29190668 | 0.91 | EGFR (0.57) | BRD4ALKFLT3EGFRJAK3 | |
| SCHEMBL29190659 | 0.91 | ALK (0.53) | BRD4ALKFLT3EGFRROS1 | |
| SCHEMBL29190605 | 0.77 | ALK (0.67) | BRD4ALKFLT3EGFRROS1 | |
| SCHEMBL29190563 | 0.77 | ALK (0.64) | ALKFLT3EGFRROS1 | |
| SCHEMBL29190642 | 0.76 | ALK (0.59) | BRD4ALKFLT3EGFRJAK1 | |
| SCHEMBL29190535 | 0.75 | ALK (0.53) | BRD4ALKFLT3EGFRJAK3 | |
| SCHEMBL29190702 | 0.75 | ALK (0.53) | BRD4ALKFLT3EGFRROS1 | |
| SCHEMBL29190583 | 0.74 | EGFR (0.59) | BRD4ALKFLT3EGFRJAK3 | |
| SCHEMBL29190637 | 0.74 | ALK (0.65) | BRD4ALKFLT3EGFRROS1 | |
| SCHEMBL29190622 | 0.74 | GLO1 (0.53) | ALKFLT3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |