Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 6/20 | 0.53 |
| ▸ | FLT3 | P36888 | 2/20 | 0.53 |
| ▸ | EGFR | P00533 | 6/20 | 0.52 |
| ▸ | BRD4 | O60885 | 4/20 | 0.49 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.46 |
| ▸ | ULK1 | O75385 | 1/20 | 0.46 |
| ▸ | ROS1 | P08922 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29190646 | 0.91 | ALK (0.47) | ALKFLT3EGFRBRD4PTK2 | |
| SCHEMBL29190605 | 0.89 | ALK (0.67) | ALKFLT3EGFRBRD4ROS1 | |
| SCHEMBL30833773 | 0.87 | BRD4 (0.47) | ALKFLT3EGFRBRD4PTK2 | |
| SCHEMBL29190535 | 0.87 | ALK (0.53) | ALKFLT3EGFRBRD4PTK2 | |
| SCHEMBL29190604 | 0.86 | ALK (0.52) | ALKFLT3EGFRBRD4ROS1 | |
| SCHEMBL30833633 | 0.85 | EGFR (0.47) | ALKFLT3EGFRBRD4PTK2 | |
| SCHEMBL29190602 | 0.85 | ALK (0.53) | ALKFLT3EGFRBRD4ROS1 | |
| SCHEMBL29190617 | 0.80 | ALK (0.68) | ALKFLT3EGFRPTK2ULK1 | |
| SCHEMBL29190594 | 0.80 | PTK2 (0.52) | ALKEGFRPTK2ULK1CDK1 | |
| SCHEMBL29190521 | 0.75 | PTK2 (0.56) | ALKFLT3EGFRPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |