Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1575491 | 0.92 | GPR119 (0.47) | KDM4EPKMEPHX1HPGDGPR119 | |
| SCHEMBL7414887 | 0.90 | GPR119 (0.49) | KDM4EPKMHPGDGPR119FAAH | |
| SCHEMBL29052765 | 0.88 | HPGD (0.45) | KDM4EPKMEPHX1HPGDGPR119 | |
| SCHEMBL24392560 | 0.88 | NR1H2 (0.47) | KDM4EPKMEPHX1HPGDGPR119 | |
| SCHEMBL7423554 | 0.88 | KDM4E (0.48) | KDM4EPKMEPHX1HPGDGPR119 | |
| SCHEMBL25841495 | 0.85 | EPHX1 (0.45) | KDM4EPKMEPHX1HPGDGPR119 | |
| SCHEMBL24510146 | 0.83 | HPGD (0.48) | KDM4EPKMEPHX1HPGDGPR119 | |
| SCHEMBL7983094 | 0.82 | KDM4E (0.44) | KDM4EPKMEPHX1HPGDGPR119 | |
| SCHEMBL7983288 | 0.81 | KDM4E (0.43) | KDM4EPKMEPHX1HPGDGPR119 | |
| SCHEMBL22300528 | 0.81 | KDM4E (0.56) | KDM4EPKMGPR119SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117883449-A | ENPP1 inhibitors and their use for the treatment of cancer | 里兰斯坦福初级大学理事会 | 2024-04-16 | — | — | CN | disclosed |
| CN-111372587-B | ENPP1 inhibitors and their use for the treatment of cancer | 里兰斯坦福初级大学理事会 | 2024-01-09 | — | — | CN | disclosed |