Biphenyl

Biphenyl

SCHEMBL2919215

C1CCC(C2CCCCC2)CC1.NC(N)=S

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
TSHR P16473 1/20 0.40
ATM Q13315 1/20 0.40
ATR Q13535 1/20 0.40
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
MGLL Q99685 1/20 0.39
LMNA P02545 1/20 0.39
GAA P10253 1/20 0.39
CTSK P43235 1/20 0.37
NOS2 P35228 1/20 0.36
EPHX1 P07099 1/20 0.36
SLC18A3 Q16572 1/20 0.36
PHGDH O43175 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.33
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL1001643 0.88 ALDH1A1 (0.47) ALDH1A1TP53CYP3A4MGLLLMNA
Biphenyl SCHEMBL10673451 0.85 ALDH1A1 (0.44) ALDH1A1TP53CYP3A4MGLLLMNA
Urea SCHEMBL28033583 0.80 ALDH1A1 (0.53) ALDH1A1CYP3A4LMNANOS2EPHX1
Biphenyl SCHEMBL159042 0.80 ALDH1A1 (0.53) ALDH1A1CYP3A4LMNANOS2EPHX1
Biphenyl SCHEMBL8588399 0.80 ALDH1A1 (0.53) ALDH1A1NOS2EPHX1SLC18A3
Biphenyl SCHEMBL11211171 0.78 ALDH1A1 (0.73) ALDH1A1NOS2EPHX1SLC18A3
Biphenyl SCHEMBL8851247 0.78 ALDH1A1 (0.73) ALDH1A1TSHRTP53CYP3A4EPHX1
SCHEMBL2999797 0.78 ALDH1A1 (0.89) ALDH1A1TSHRNOS2EPHX1SLC18A3
SCHEMBL231054 0.78 ALDH1A1 (0.89) ALDH1A1TSHRNOS2EPHX1SLC18A3
SCHEMBL22284064 0.78 ALDH1A1 (0.89) ALDH1A1TSHRNOS2EPHX1SLC18A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3342393-B1 DENTAL CEMENT G C DENTAL IND CORP (JP) 2023-11-29 EP claimed
CN-115449136-A Accelerator composition of rubber nanocomposite and preparation method and application thereof 浙江大学 2022-12-09 CN claimed
CN-112375919-B Method for directly recovering gold in thiosulfate system 昆明理工大学 2022-07-08 CN claimed
CN-112375919-A Method for directly recovering gold in thiosulfate system 昆明理工大学 2021-02-19 CN claimed
CN-109651149-A A method of preparing 1,2- cyclohexane cyclohexanedimethanodibasic ester or phthalic acid ester 中国科学院大连化学物理研究所 2019-04-19 CN claimed
CN-109516930-A The processing method of sulfur waste sulphur in a kind of N, N '-dicyclohexylcarbodiimide 山东汇海医药化工有限公司 2019-03-26 CN claimed
CN-109336786-A It is a kind of that hydrogen peroxide is used to synthesize N, the method for N '-dicyclohexylcarbodiimide as oxidant 山东汇海医药化工有限公司 2019-02-15 CN claimed
CN-108299241-A A kind of method for oxidation of N, N '-dicyclohexyl thiourea 山东汇海医药化工有限公司 2018-07-20 CN claimed
CN-108117489-A A kind of method that ester is prepared by crotonaldehyde and formaldehyde 中国科学院大连化学物理研究所 2018-06-05 CN claimed
CN-108117478-A The preparation method of 1,4 cyclohexane dimethanol or 1,4 cyclohexanedicarboxylic acid 中国科学院大连化学物理研究所 2018-06-05 CN claimed
CN-103102358-B A kind of cephalosporin compound, its crystal and its production and use GUANGZHOU BAIYUNSHAN PHARMACEUTICAL CO., LTD. (CN) 2015-09-02 CN claimed
CN-104193653-A Novel synthesis method of N, N'-dicyclohexylcarbo-diimide SHANDONG HUIHAI PHARMACEUTICALS & CHEMICALS CO LTD 2014-12-10 CN claimed
CN-103787529-A Method for treating DCC (N,N'-dicyclohexylcarbodiimide) oxidation wastewater SHANDONG HUIHAI PHARMACEUTICALS & CHEMICALS CO LTD 2014-05-14 CN claimed
CN-102731357-B Preparation method of high purity N,N'-dicyclohexylthiourea SHANDONG JINCHENG PHARMACEUTICAL & CHEMICAL CO LTD 2014-02-12 CN claimed
CN-103102358-A Cephalosporin compound, crystal thereof, and preparation method and application thereof GUANGZHOU BAIYUNSHAN CHEMICAL PHARMACEUTICAL FACTORY GUANGZHOU BAIYUNSHAN PHARMACEUTICAL CO LTD 2013-05-15 CN claimed
CN-102731357-A Preparation method of high purity N,N'-dicyclohexylthiourea SHANDONG JINCHENG PHARMACEUTICAL & CHEMICAL CO LTD 2012-10-17 CN claimed
CN-100434416-C Production technique of N,N'-dicyclo hexylcar bodiimide SHANDONG JINCHENG PHARMACEUTIC (CN) 2008-11-19 CN claimed
CN-101096349-A Production technique of N,N'-dicyclo hexylcar bodiimide SHANDONG JINCHENG PHARMACEUTIC (CN) 2008-01-02 CN claimed
CN-1962630-A N'-dicyclohexyl thiourea preparation method UNIV ZHEJIANG (CN) 2007-05-16 CN claimed
CN-1962631-A N, N'- dicyclohexyl thiourea microwave synthesis method UNIV ZHEJIANG (CN) 2007-05-16 CN claimed