Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL325416 | 0.93 | TSHR (0.56) | TSHRALDH1A1HPGDPOLBACACB | |
| SCHEMBL8196999 | 0.81 | TSHR (0.52) | TSHRHPGDACACBZDHHC20ZDHHC2 | |
| SCHEMBL27193048 | 0.80 | ZDHHC20 (0.50) | TSHRALDH1A1ACACBZDHHC20ZDHHC2 | |
| SCHEMBL7632691 | 0.79 | ZDHHC20 (0.53) | TSHRALDH1A1ZDHHC20ZDHHC2KMT2A | |
| SCHEMBL36597 | 0.79 | ZDHHC20 (0.53) | TSHRALDH1A1ZDHHC20ZDHHC2KMT2A | |
| SCHEMBL8765444 | 0.79 | ZDHHC20 (0.53) | TSHRALDH1A1ZDHHC20ZDHHC2KMT2A | |
| SCHEMBL8966072 | 0.79 | ZDHHC20 (0.53) | TSHRALDH1A1ZDHHC20ZDHHC2KMT2A | |
| SCHEMBL10875526 | 0.79 | ZDHHC20 (0.53) | TSHRALDH1A1ZDHHC20ZDHHC2KMT2A | |
| SCHEMBL13224427 | 0.79 | ZDHHC20 (0.53) | TSHRALDH1A1ZDHHC20ZDHHC2KMT2A | |
| SCHEMBL16584963 | 0.79 | ZDHHC20 (0.53) | TSHRALDH1A1ZDHHC20ZDHHC2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117585963-A | Shrinkage-reducing anti-cracking type large-volume concrete and preparation method thereof | 中建商品混凝土有限公司 | 2024-02-23 | — | — | CN | claimed |