SCHEMBL325416

SCHEMBL325416

C=CC(=O)NC(C)CCC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.56
ALDH1A1 P00352 6/20 0.42
HPGD P15428 1/20 0.42
POLB P06746 1/20 0.42
ACACB O00763 2/20 0.41
ZDHHC20 Q5W0Z9 1/20 0.41
ZDHHC2 Q9UIJ5 1/20 0.41
KMT2A Q03164 3/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
TAS1R3 Q7RTX0 3/20 0.39
TAS1R1 Q7RTX1 3/20 0.39
MAPK1 P28482 2/20 0.38
MEN1 O00255 1/20 0.38
FAAH O00519 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
LMNA P02545 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
THRB P10828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29192530 0.93 TSHR (0.48) TSHRALDH1A1HPGDPOLBACACB
SCHEMBL8196999 0.88 TSHR (0.52) TSHRHPGDACACBZDHHC20ZDHHC2
SCHEMBL27193048 0.86 ZDHHC20 (0.50) TSHRALDH1A1ACACBZDHHC20ZDHHC2
SCHEMBL10875526 0.85 ZDHHC20 (0.53) TSHRALDH1A1ZDHHC20ZDHHC2KMT2A
SCHEMBL7632691 0.85 ZDHHC20 (0.53) TSHRALDH1A1ZDHHC20ZDHHC2KMT2A
SCHEMBL8765444 0.85 ZDHHC20 (0.53) TSHRALDH1A1ZDHHC20ZDHHC2KMT2A
SCHEMBL8766092 0.85 ZDHHC20 (0.53) TSHRALDH1A1ZDHHC20ZDHHC2KMT2A
SCHEMBL13224427 0.85 ZDHHC20 (0.53) TSHRALDH1A1ZDHHC20ZDHHC2KMT2A
SCHEMBL36597 0.85 ZDHHC20 (0.53) TSHRALDH1A1ZDHHC20ZDHHC2KMT2A
SCHEMBL8966072 0.85 ZDHHC20 (0.53) TSHRALDH1A1ZDHHC20ZDHHC2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025024325-A2 ALL-ACRYLIC TRIBLOCK AND TETRABLOCK COPOLYMERS HAVING A LACTAM MOIETY AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2025-01-30 WO claimed
CN-104812790-B Organopolysiloxane graft polymers 花王株式会社 2019-04-12 CN claimed
EP-2927253-B1 ORGANOPOLYSILOXANE GRAFT POLYMER KAO CORP (JP) 2018-09-12 EP claimed
US-9351920-B2 Organopolysiloxane graft polymer KAO CORPORATION (JP) 2016-05-31 US claimed
US-20150297498-A1 ORGANOPOLYSILOXANE GRAFT POLYMER KAO CORPORATION (JP) 2015-10-22 US claimed
EP-2927253-A1 ORGANOPOLYSILOXANE GRAFT POLYMER Kao Corporation (JP) 2015-10-07 EP claimed
CN-104812790-A Organopolysiloxane graft polymer KAO CORP 2015-07-29 CN claimed
EP-0966948-B1 Cosmetic composition containing an anionic polymer and an acrylic terpolymer and use of said composition for treating keratinic materials OREAL (FR) 2002-05-22 EP claimed
EP-0966948-A1 Cosmetic composition containing an anionic polymer and an acrylic terpolymer and use of said composition for treating keratinic materials L'OREAL (FR) 1999-12-29 EP claimed
EP-3935113-B1 AQUEOUS COATING COMPOSITION ALLNEX NETHERLANDS BV (NL) 2026-05-06 EP disclosed
US-12534634-B2 Aqueous coating composition ALLNEX NETHERLANDS (NL) 2026-01-27 US disclosed
WO-2025098970-A1 WATERBORNE COATING COMPOSITION ALLNEX NETHERLANDS B.V. (NL) 2025-05-15 WO disclosed
US-20250143359-A1 COMPOUNDS THAT MODULATE GPR92 RECEPTOR ACTIVITY AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2025-05-08 US disclosed
WO-2025024325-A2 ALL-ACRYLIC TRIBLOCK AND TETRABLOCK COPOLYMERS HAVING A LACTAM MOIETY AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2025-01-30 WO disclosed
WO-1995003029-A1 HAIR FIXING COSMETIC COMPOSITIONS WITH IMPROVED SETTING PROPERTIES L'OREAL (FR) 1995-02-02 WO disclosed
EP-0635258-A1 Cosmetic compositions with improved fixing power L'OREAL (FR) 1995-01-25 EP disclosed
EP-0477053-B1 Cosmetic hair composition containing a film-forming polymer and a silicon incorporated in a microdispersion of wax, and its process for cosmetic treatment OREAL (FR) 1994-01-12 EP disclosed
US-5275811-A Terpolymer resin of vinyl ester, acrylamide and maleate ISP INVESTMENTS INC. (US) 1994-01-04 US disclosed
US-5196495-A Hair spray; terpolymer of a vinyl ester, alkyl maleate half ester and a substituted acrylamide ISP INVESTMENTS INC. (US) 1993-03-23 US disclosed
EP-0477053-A1 Cosmetic hair composition containing a film-forming polymer and a silicon incorporated in a microdispersion of wax, and its process for cosmetic treatment L'OREAL (FR) 1992-03-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150297498-A1 ORGANOPOLYSILOXANE GRAFT POLYMER IDUA, PIGS, GMNN TSHR 2848/4885ALDH1A1 2410/4885HPGD 1799/4885
US-12534634-B2 Aqueous coating composition CHRM1, CD274, CHRM2 TSHR 2979/4885ALDH1A1 839/4885HPGD 2937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.