Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 4/20 | 0.33 |
| ▸ | AURKA | O14965 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30358920 | 1.00 | PDE10A (0.40) | PDE10ACHEK1TRPV4SMN1; SMN2TSHR | |
| SCHEMBL929688 | 0.85 | PDE10A (0.40) | PDE10ACHEK1TRPV4SMN1; SMN2TSHR | |
| SCHEMBL30018060 | 0.85 | PDE10A (0.40) | PDE10ACHEK1TRPV4SMN1; SMN2TSHR | |
| SCHEMBL14183066 | 0.79 | PDE10A (0.40) | PDE10ACHEK1TRPV4SMN1; SMN2TSHR | |
| SCHEMBL31045864 | 0.78 | PDE10A (0.43) | PDE10ACHEK1TRPV4SMN1; SMN2TSHR | |
| SCHEMBL17949359 | 0.76 | TRPV4 (0.41) | TRPV4CA2CHKA | |
| SCHEMBL22161741 | 0.76 | PDE10A (0.40) | PDE10ACHEK1TRPV4SMN1; SMN2TSHR | |
| SCHEMBL30868926 | 0.75 | PDE10A (0.41) | PDE10ACHEK1TRPV4SMN1; SMN2TSHR | |
| SCHEMBL7919171 | 0.75 | PDE10A (0.38) | PDE10ACHEK1TRPV4SMN1; SMN2TSHR | |
| SCHEMBL1506552 | 0.75 | TRPV4 (0.38) | TRPV4CA2CHKAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651699-A | Compounds and compositions for the treatment of coronavirus related diseases | 诺华股份有限公司 | 2024-03-05 | — | — | CN | disclosed |