Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7916902 | 0.85 | PDE10A (0.40) | PDE10AAXLCHEK1MAPTHCRTR1 | |
| SCHEMBL17711404 | 0.83 | PDE10A (0.36) | PDE10AAXLMAPTHCRTR1ALDH1A1 | |
| SCHEMBL30778487 | 0.81 | LRRK2 (0.36) | TRPV4PTGS1PTGS2TSHRCA2 | |
| SCHEMBL14183066 | 0.79 | PDE10A (0.40) | PDE10ACHEK1HCRTR1TRPV4ALDH1A1 | |
| SCHEMBL30778502 | 0.79 | RXRA (0.33) | L3MBTL1TRPV4CA2CHKA | |
| SCHEMBL30358920 | 0.78 | PDE10A (0.40) | PDE10ACHEK1HCRTR1KDM4EHPGD | |
| SCHEMBL29192556 | 0.78 | PDE10A (0.40) | PDE10ACHEK1HCRTR1KDM4EHPGD | |
| SCHEMBL16213734 | 0.76 | AXL (0.42) | PDE10AAXLMAPTNPSR1L3MBTL1 | |
| SCHEMBL31057600 | 0.76 | AXL (0.42) | PDE10AAXLMAPTNPSR1L3MBTL1 | |
| SCHEMBL22161741 | 0.76 | PDE10A (0.40) | PDE10ACHEK1HCRTR1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4680336-A1 | AMIDE DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF | Ventus Therapeutics U.S., Inc. (US) | 2026-01-21 | — | — | EP | disclosed |
| WO-2024196788-A1 | AMIDE DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2024-09-26 | — | — | WO | disclosed |