Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29192572 | 0.99 | ADRA2A (0.42) | ADRA2AADRA2BADRA2CADRA1AHDAC6 | |
| Hydrochloric Acid SCHEMBL29192526 | 0.80 | ADRA2A (0.42) | ADRA2AADRA2BADRA2CADRA1AHDAC6 | |
| SCHEMBL29192555 | 0.80 | HDAC6 (0.39) | ADRA2AADRA2BADRA2CADRA1AHDAC6 | |
| SCHEMBL30797446 | 0.78 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CADRA1AHDAC6 | |
| SCHEMBL29192431 | 0.78 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CADRA1AHDAC6 | |
| SCHEMBL29192559 | 0.76 | LRRK2 (0.33) | ALDH1A1CTSC | |
| SCHEMBL29192436 | 0.76 | ADRA2A (0.35) | ADRA2AADRA2BADRA2CADRA1AHDAC6 | |
| Hydrochloric Acid SCHEMBL29192498 | 0.75 | ADRA2A (0.41) | ADRA2AADRA2BADRA2CADRA1AHDAC6 | |
| Hydrochloric Acid SCHEMBL29192495 | 0.75 | ADRA2A (0.41) | ADRA2AADRA2BADRA2CADRA1AHDAC6 | |
| SCHEMBL2477411 | 0.69 | ADRA2A (0.58) | ADRA2AADRA2BADRA2CADRA1AHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651699-A | Compounds and compositions for the treatment of coronavirus related diseases | 诺华股份有限公司 | 2024-03-05 | — | — | CN | disclosed |