Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | LGMN | Q99538 | 4/20 | 0.32 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 5/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29192491 | 0.84 | LGMN (0.36) | LRRK2ALDH1A1NQO2MTNR1AMTNR1B | |
| SCHEMBL29192415 | 0.79 | ACACB (0.34) | ALDH1A1NQO2MTNR1AMTNR1BLGMN | |
| SCHEMBL30358841 | 0.79 | PDE4B (0.39) | ALDH1A1MAPK8MAPK9PDE4BMAPK10 | |
| SCHEMBL29192576 | 0.76 | ADRA2A (0.43) | ALDH1A1CTSC | |
| Hydrochloric Acid SCHEMBL29192572 | 0.75 | ADRA2A (0.42) | ALDH1A1CTSC | |
| SCHEMBL30032674 | 0.69 | G6PD (0.45) | ALDH1A1NQO2MTNR1AMTNR1BCCNC | |
| SCHEMBL29192477 | 0.69 | G6PD (0.45) | ALDH1A1NQO2MTNR1AMTNR1BCCNC | |
| SCHEMBL17437243 | 0.66 | LMNA (0.42) | LRRK2ALDH1A1CCNCCDK8 | |
| SCHEMBL29192548 | 0.66 | CCNC (0.40) | NQO2MTNR1AMTNR1BCCNCCDK8 | |
| SCHEMBL31464840 | 0.65 | GPR119 (0.38) | ALDH1A1NQO2MTNR1AMTNR1BPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4373814-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CORONAVIRAL RELATED DISEASES | Novartis AG (CH) | 2024-05-29 | — | — | EP | disclosed |
| CN-117651699-A | Compounds and compositions for the treatment of coronavirus related diseases | 诺华股份有限公司 | 2024-03-05 | — | — | CN | disclosed |
| WO-2023002409-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CORONAVIRAL RELATED DISEASES | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |