Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | HPGD | P15428 | 6/20 | 0.51 |
| ▸ | KHK | P50053 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30762528 | 0.72 | KMT2A (0.55) | ALDH1A1HPGDKHKADORA2AKDM4E | |
| SCHEMBL30762659 | 0.71 | ALDH1A1 (0.51) | ALDH1A1HPGDKHKADORA2AKDM4E | |
| SCHEMBL23327900 | 0.71 | KDM4E (0.63) | ALDH1A1HPGDKHKKDM4EHSD17B10 | |
| SCHEMBL31326608 | 0.70 | TSHR (0.47) | ALDH1A1HPGDKHKKDM4EHTT | |
| SCHEMBL30762425 | 0.69 | ALDH1A1 (0.46) | ALDH1A1HPGDKHKADORA2AKDM4E | |
| SCHEMBL30762379 | 0.68 | ALDH1A1 (0.48) | ALDH1A1HPGDKHKKDM4EHSD17B10 | |
| SCHEMBL11702372 | 0.68 | ALDH1A1 (0.57) | ALDH1A1HPGDKHKADORA2AKDM4E | |
| SCHEMBL13829597 | 0.67 | ADORA2A (0.59) | ALDH1A1HPGDKHKADORA2AKDM4E | |
| SCHEMBL11753128 | 0.67 | ALDH1A1 (0.76) | ALDH1A1HPGDKHKKDM4EHSD17B10 | |
| SCHEMBL22122610 | 0.67 | POLB (0.47) | ALDH1A1HPGDKHKKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110325515-B | Quinoxaline compounds as inhibitors of type III receptor tyrosine kinase | 财团法人生物技术开发中心 | 2023-06-20 | — | — | CN | claimed |