Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | KHK | P50053 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30762641 | 0.81 | KMT2A (0.56) | KMT2APOLBALDH1A1HPGDKHK | |
| SCHEMBL30762357 | 0.78 | ALDH1A1 (0.52) | KMT2APOLBALDH1A1HPGDKHK | |
| SCHEMBL30762659 | 0.78 | ALDH1A1 (0.51) | KMT2AALDH1A1HPGDKHKMEN1 | |
| SCHEMBL30762361 | 0.75 | ALDH1A1 (0.49) | KMT2APOLBALDH1A1HPGDKHK | |
| SCHEMBL29193671 | 0.72 | ALDH1A1 (0.51) | KMT2APOLBALDH1A1HPGDKHK | |
| SCHEMBL30762625 | 0.71 | ALDH1A1 (0.50) | KMT2APOLBALDH1A1HPGDKHK | |
| SCHEMBL21404458 | 0.71 | KMT2A (0.60) | KMT2APOLBALDH1A1HPGDMEN1 | |
| SCHEMBL31353546 | 0.70 | KMT2A (0.44) | KMT2APOLBALDH1A1HPGDMEN1 | |
| SCHEMBL23327900 | 0.70 | KDM4E (0.63) | POLBALDH1A1HPGDKHKNPC1 | |
| SCHEMBL30762379 | 0.70 | ALDH1A1 (0.48) | KMT2APOLBALDH1A1HPGDKHK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026423-A1 | SUBSTITUTED QUINOLINE DERIVATIVES AS PI3K INHIBITORS | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |