SCHEMBL29194166

SCHEMBL29194166

CC(=CC1c2ccccc2-c2ccccc21)C(=O)OC(=O)Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.42
CYP1A2 P05177 1/20 0.34
TSHR P16473 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 3/20 0.33
HDAC3 O15379 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
HDAC9 Q9UKV0 1/20 0.33
HDAC5 Q9UQL6 1/20 0.33
NCOR2 Q9Y618 1/20 0.33
GPR3 P46089 1/20 0.33
GAA P10253 1/20 0.32
LMNA P02545 2/20 0.31
MEN1 O00255 2/20 0.31
ALDH1A1 P00352 4/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27492862 0.84 POLB (0.41) POLBCYP1A2TSHRCYP2C19KMT2A
SCHEMBL31115247 0.83 POLB (0.46) POLBKMT2AHDAC3HDAC4HDAC7
SCHEMBL5482288 0.77 POLB (0.46) POLBCYP1A2TSHRKMT2AHDAC3
SCHEMBL5869639 0.77 POLB (0.46) POLBCYP1A2TSHRKMT2AHDAC3
SCHEMBL29182398 0.76 POLB (0.38) POLBCYP1A2TSHRCYP2C19KMT2A
SCHEMBL28588442 0.74 POLB (0.39) POLBCYP1A2TSHRCYP2C19KMT2A
SCHEMBL28956322 0.72 ALDH1A1 (0.46) POLBALDH1A1
SCHEMBL20497207 0.67 POLB (0.55) POLBCYP1A2TSHRKMT2AHDAC3
SCHEMBL29043963 0.67 POLB (0.42) POLBCYP1A2TSHRKMT2AHDAC3
SCHEMBL3751216 0.66 HDAC3 (0.41) POLBCYP1A2TSHRKMT2AHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109020992-B Method for preparing beta-type mono/bis sweet wormwood alkyl ether amine maleate in stereoselective manner 华东理工大学 2024-04-12 CN disclosed