⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochlorthiazide SCHEMBL450348 | 0.96 | — | — | |
| Hydrochlorthiazide SCHEMBL9336266 | 0.96 | — | — | |
| Hydrochlorthiazide SCHEMBL6291 | 0.96 | — | — | |
| Hydrochlorthiazide SCHEMBL3110285 | 0.96 | — | — | |
| Hydrochlorthiazide SCHEMBL25294605 | 0.93 | — | — | |
| Hydrochlorthiazide SCHEMBL271146 | 0.93 | — | — | |
| Hydrochlorthiazide SCHEMBL250706 | 0.93 | — | — | |
| Hydrochlorthiazide SCHEMBL2498526 | 0.93 | — | — | |
| Hydrochlorthiazide SCHEMBL2259998 | 0.93 | — | — | |
| Hydrochlorthiazide SCHEMBL8981983 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594937-B1 | THERMAL LIQUIDS PROVIDING GLASS CORROSION PROTECTION ESPECIALLY FOR SOLAR SYSTEMS | BASF SE (DE) | 2012-03-21 | — | — | EP | claimed |
| EP-1634937-B1 | Silicate-Free, organic acids and carbamate based cooling liquids with improved corrosion properties | CLARIANT PRODUKTE DEUTSCHLAND (DE) | 2008-04-23 | — | — | EP | claimed |
| CN-100372907-C | Thermal liquids providing glass corrosion protection especially for solar systems | BASF AG (DE) | 2008-03-05 | — | — | CN | claimed |
| US-20060180793-A1 | Thermal liquids providing glass corrosion protection especially for solar systems | BASF AKTIENGESELLSCHAFT (DE) | 2006-08-17 | — | — | US | claimed |
| CN-1751108-A | Thermal liquids providing glass corrosion protection especially for solar systems | BASF AG (DE) | 2006-03-22 | — | — | CN | claimed |
| US-20060033076-A1 | Silicate-free cooling liquids based on organic acids and carbamates having improved corrosion properties | CLARIANT GMBH | 2006-02-16 | — | — | US | claimed |
| CN-1733862-A | Silicateless cool liquid based on organic acid and carbamate having improved corrosion behavior | CLARIANT GMBH (DE) | 2006-02-15 | — | — | CN | claimed |
| CN-1218009-C | Antifreeze concentrates on the basis of dicarboxylic acids, molbdate and triazoles or thiazoles and coolant compositions containing these concentrates | BASF AG (DE) | 2005-09-07 | — | — | CN | claimed |
| EP-0816467-B1 | Silicate, borate and nitrate free antifreeze concentrate and refrigerant comprising said antifreeze | BASF AG (DE) | 2004-03-10 | — | — | EP | claimed |
| CN-1384862-A | Antifreeze concentrates on the basis of dicarboxylic acids, molbdate and triazoles or thiazoles and coolant compositions containing these concentrates | BASF AG (DE) | 2002-12-11 | — | — | CN | claimed |
| US-6080331-A | ANTIFREEZE CONCENTRATES BASED ON ALKYLENE GLYCOLS INCLUDING AN INHIBITOR CONTAINING TWO MONOCARBOXYLIC ACIDS IN THE FORM OF ALKALI OR AMMONIUM SALTS, AND HYROXYAROMATIC ACID, AND ATLEAST ONE HYDROCARBON/TRAIZOLE AND/OR HYDROCARBON-THIAZOLE | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-27 | — | — | US | claimed |
| US-6045719-A | COOLING CIRCUITS OF INTERNAL COMBUSTION ENGINES, AS IN CARS; RAISE THE HIGH-TEMPERATURE PROTECTION OF NONFERROUS METALS BY CUSTOMARY INHIBITOR SYSTEMS WITHOUT A DROP IN PROTECTION FOR THE OTHER METALS, ESPECIALLY ALUMINUM ALLOYS | BASF AKTIENGESELLSCHAFT (DE) | 2000-04-04 | — | — | US | claimed |
| EP-0880566-B1 | USE OF QUATERNIZED IMIDAZOLES AS NONFERROUS METAL CORROSION INHIBITORS AND ANTIFREEZE CONCENTRATES AND COOLANT COMPOSITIONS CONTAINING SAID CORROSION INHIBITORS | BASF AG (DE) | 1999-11-10 | — | — | EP | claimed |
| CN-1172144-A | Silicate-, borate- and nitrate-free antifreeze concentrates and coolant compositions comprising them | BASF AG (DE) | 1998-02-04 | — | — | CN | claimed |
| CN-102421867-A | Antifreeze concentrate and coolant composition and method of making same | CHEVRON USA INC | 2012-04-18 | — | — | CN | disclosed |
| EP-2427529-A2 | ANTIFREEZE CONCENTRATE AND COOLANT COMPOSITIONS AND PREPARATION THEREOF | Chevron U.S.A. Incorporated (US) | 2012-03-14 | — | — | EP | disclosed |
| US-8057695-B2 | Antifreeze concentrate and coolant compositions and preparation thereof | CHEVRON U.S.A. INC. (US) | 2011-11-15 | — | — | US | disclosed |
| US-6080331-A | ANTIFREEZE CONCENTRATES BASED ON ALKYLENE GLYCOLS INCLUDING AN INHIBITOR CONTAINING TWO MONOCARBOXYLIC ACIDS IN THE FORM OF ALKALI OR AMMONIUM SALTS, AND HYROXYAROMATIC ACID, AND ATLEAST ONE HYDROCARBON/TRAIZOLE AND/OR HYDROCARBON-THIAZOLE | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-27 | — | — | US | disclosed |
| US-6045719-A | COOLING CIRCUITS OF INTERNAL COMBUSTION ENGINES, AS IN CARS; RAISE THE HIGH-TEMPERATURE PROTECTION OF NONFERROUS METALS BY CUSTOMARY INHIBITOR SYSTEMS WITHOUT A DROP IN PROTECTION FOR THE OTHER METALS, ESPECIALLY ALUMINUM ALLOYS | BASF AKTIENGESELLSCHAFT (DE) | 2000-04-04 | — | — | US | disclosed |
| CN-1172144-A | Silicate-, borate- and nitrate-free antifreeze concentrates and coolant compositions comprising them | BASF AG (DE) | 1998-02-04 | — | — | CN | disclosed |