⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochlorthiazide SCHEMBL3110285 | 1.00 | — | — | |
| Hydrochlorthiazide SCHEMBL9336266 | 1.00 | — | — | |
| Hydrochlorthiazide SCHEMBL450348 | 1.00 | — | — | |
| Hydrochlorthiazide SCHEMBL271146 | 0.96 | — | — | |
| Hydrochlorthiazide SCHEMBL8981983 | 0.96 | — | — | |
| Hydrochlorthiazide SCHEMBL25294605 | 0.96 | — | — | |
| Hydrochlorthiazide SCHEMBL250706 | 0.96 | — | — | |
| Hydrochlorthiazide SCHEMBL291944 | 0.96 | — | — | |
| Hydrochlorthiazide SCHEMBL2498526 | 0.96 | — | — | |
| Hydrochlorthiazide SCHEMBL704488 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 350903 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12187715-B2 | Small molecule activators of Tie-2 | EyePoint Pharmaceuticals, Inc. (US) | 2025-01-07 | — | — | US | claimed |
| CN-119264518-A | Carbon-silicon composite material and preparation method and application thereof | 广东电网有限责任公司 | 2025-01-07 | — | — | CN | claimed |
| CN-115786915-B | Copper etching solution for semiconductor packaging and etching method | 江阴江化微电子材料股份有限公司 | 2025-01-03 | — | — | CN | claimed |
| CN-119220356-A | Preparation method of cleaning liquid | 上海新阳半导体材料股份有限公司 | 2024-12-31 | — | — | CN | claimed |
| US-20240425539-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2024-12-26 | — | — | US | claimed |
| WO-2024264012-A1 | BIOAVAILABILITY ENHANCING IONIC LIQUID FORMULATIONS INCLUDING ANTHELMINITIC BENZIMIDAZOLE COMPOUNDS AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2024-12-26 | — | — | WO | claimed |
| CN-119176796-A | Amide disubstituted pyridine or pyridazine compounds | 百时美施贵宝公司 | 2024-12-24 | — | — | CN | claimed |
| CN-119144062-A | High-dynamic anti-slip rubber sole and preparation method thereof | 安踏（中国）有限公司 | 2024-12-17 | — | — | CN | claimed |
| US-20240407418-A1 | COMPOSITIONS AND METHODS FOR PRODUCING AROMAS | Nourish Ingredients Pty Ltd (AU) | 2024-12-12 | — | — | US | claimed |
| US-20240415004-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2024-12-12 | — | — | US | claimed |
| US-3953215-A | X-RAY FILM | FUJI PHOTO FILM CO., LTD. (JA) | 1976-04-27 | — | — | US | claimed |
| US-3947459-A | FROM ALKALI SALT OF MERCAPTOTHIAZOLES, AMINES AND BLEACH | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-03-30 | — | — | US | claimed |
| US-3945837-A | RESINOUS BINDER, HYDROCARBON SOLVENT, MODIFIED DYE | SAKURA COLOR PRODUCTS CORPORATION (JA) | 1976-03-23 | — | — | US | claimed |
| US-3945832-A | Fogged, direct-positive silver halide emulsion containing desensitizers and a dimethine optical sensitizing dye | FUJI PHOTO FILM CO., LTD. (JA) | 1976-03-23 | — | — | US | claimed |
| US-3945991-A | Heterocyclic azo compounds containing a quaternated hydrazide group | CIBA-GEIGY AG (CH) | 1976-03-23 | — | — | US | claimed |
| US-3945989-A | Fluoro triazine containing water insoluble azo dyestuff | CIBA-GEIGY AG (CH) | 1976-03-23 | — | — | US | claimed |
| US-3936308-A | Photographic emulsions containing methine dyes having a 1H-imidazo[4,5-b]pyrazine nucleus | EASTMAN KODAK COMPANY (US) | 1976-02-03 | — | — | US | claimed |
| US-3936429-A | Reactive polymer | FUJI PHOTO FILM CO., LTD. (JA) | 1976-02-03 | — | — | US | claimed |
| US-3933664-A | Organic photoconductive toner materials | CANON INC. (JA) | 1976-01-20 | — | — | US | claimed |
| US-3932400-A | CARDIOVASCULAR DISORDERS, ANTIARRHYTHMIA AGENTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-01-13 | — | — | US | claimed |