Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.45 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30245649 | 1.00 | LTA4H (0.48) | LTA4HALDH1A1TSHRSMN1; SMN2NPSR1 | |
| SCHEMBL29194615 | 0.95 | ALDH1A1 (0.47) | LTA4HALDH1A1TSHRSMN1; SMN2NPSR1 | |
| SCHEMBL30244868 | 0.95 | ALDH1A1 (0.47) | LTA4HALDH1A1TSHRSMN1; SMN2NPSR1 | |
| SCHEMBL30245572 | 0.94 | ALDH1A1 (0.54) | LTA4HALDH1A1TSHRSMN1; SMN2NPSR1 | |
| SCHEMBL25252979 | 0.91 | LTA4H (0.49) | LTA4HALDH1A1TSHRSMN1; SMN2NPSR1 | |
| SCHEMBL30245121 | 0.91 | LTA4H (0.49) | LTA4HALDH1A1TSHRSMN1; SMN2NPSR1 | |
| SCHEMBL30245317 | 0.91 | ALDH1A1 (0.46) | LTA4HALDH1A1TSHRSMN1; SMN2NPSR1 | |
| SCHEMBL29194445 | 0.91 | ALDH1A1 (0.46) | LTA4HALDH1A1TSHRSMN1; SMN2NPSR1 | |
| SCHEMBL30245817 | 0.90 | ALDH1A1 (0.45) | ALDH1A1TSHRSMN1; SMN2NPSR1STAT6 | |
| SCHEMBL25424093 | 0.89 | LTA4H (0.44) | LTA4HALDH1A1TSHRSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | claimed |
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | disclosed |