Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30856623 | 1.00 | EPAS1 (0.34) | EPAS1S1PR4MAPTMEN1NPC1 | |
| SCHEMBL31651954 | 0.85 | MAPT (0.35) | S1PR4MAPTMEN1NPC1LMNA | |
| SCHEMBL30856679 | 0.76 | KMT2A (0.41) | EPAS1MAPTMEN1RAB9AKMT2A | |
| SCHEMBL29195489 | 0.76 | KMT2A (0.41) | EPAS1MAPTMEN1RAB9AKMT2A | |
| SCHEMBL195009 | 0.75 | MAPT (0.40) | S1PR4MAPTMEN1NPC1LMNA | |
| SCHEMBL19754794 | 0.75 | MAPT (0.36) | S1PR4MAPTMEN1NPC1LMNA | |
| SCHEMBL31463515 | 0.70 | CYP19A1 (0.41) | MAPTMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL26647353 | 0.70 | NPC1 (0.40) | S1PR4MAPTMEN1NPC1LMNA | |
| SCHEMBL20189884 | 0.69 | CYP1A2 (0.46) | EPAS1 | |
| SCHEMBL30448458 | 0.69 | CYP1A2 (0.46) | EPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917405-A | KIF18A protein inhibitors | 杭州邦顺制药有限公司 | 2024-04-23 | — | — | CN | disclosed |