Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MAP3K12 | Q12852 | 5/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29195489 | 1.00 | KMT2A (0.41) | KMT2AHTTMETEPAS1DYRK1A | |
| SCHEMBL31309434 | 0.82 | KMT2A (0.47) | KMT2AHTTMETDYRK1AMAP4K3 | |
| SCHEMBL2654905 | 0.80 | MAP4K3 (0.46) | KMT2AHTTMETDYRK1AMAP4K3 | |
| SCHEMBL15616478 | 0.78 | KMT2A (0.43) | KMT2AHTTMETDYRK1AMAP4K3 | |
| SCHEMBL29195504 | 0.76 | EPAS1 (0.34) | KMT2AEPAS1MEN1MAPTRAB9A | |
| SCHEMBL30856623 | 0.76 | EPAS1 (0.34) | KMT2AEPAS1MEN1MAPTRAB9A | |
| SCHEMBL30448458 | 0.74 | CYP1A2 (0.46) | EPAS1 | |
| SCHEMBL20189884 | 0.74 | CYP1A2 (0.46) | EPAS1 | |
| SCHEMBL24723259 | 0.74 | AKT1 (0.39) | KMT2AHTTDYRK1AMAP3K12 | |
| SCHEMBL16858563 | 0.73 | CYP1A2 (0.36) | EPAS1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917405-A | KIF18A protein inhibitors | 杭州邦顺制药有限公司 | 2024-04-23 | — | — | CN | disclosed |