Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29195755 | 0.90 | ALDH1A1 (0.39) | LMNAADORA2AADORA2BALDH1A1HPGD | |
| SCHEMBL29195833 | 0.86 | ALDH1A1 (0.41) | LMNAALDH1A1HPGDALOX15CASP1 | |
| SCHEMBL29195848 | 0.86 | P2RX7 (0.41) | P2RX7LMNAADORA2AADORA2BALDH1A1 | |
| SCHEMBL29195761 | 0.86 | P2RX7 (0.45) | P2RX7 | |
| SCHEMBL29195810 | 0.85 | P2RX7 (0.44) | P2RX7LMNAADORA2AADORA2BALDH1A1 | |
| SCHEMBL29195799 | 0.85 | P2RX7 (0.39) | P2RX7LMNAADORA2AADORA2BALDH1A1 | |
| SCHEMBL29195769 | 0.85 | P2RX7 (0.39) | P2RX7LMNAADORA2AADORA2BALDH1A1 | |
| SCHEMBL29195800 | 0.83 | P2RX7 (0.40) | P2RX7LMNAADORA2AADORA2BALDH1A1 | |
| SCHEMBL29195783 | 0.81 | TP53 (0.42) | P2RX7LMNAADORA2AADORA2BALDH1A1 | |
| SCHEMBL30309029 | 0.81 | P2RX7 (0.38) | P2RX7LMNAADORA2AADORA2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881675-A | 2, 4-dihydro-3H-1, 2, 4-triazol-3-one P2X7 antagonists | 布雷耶疗法有限公司 | 2024-04-12 | — | — | CN | disclosed |