Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30753728 | 0.91 | MAPT (0.41) | MAPTMEN1KMT2APYCR1LMNA | |
| SCHEMBL29279069 | 0.89 | MAPT (0.40) | MAPTMEN1KMT2APYCR1LMNA | |
| SCHEMBL38660409 | 0.84 | CYP1A2 (0.41) | MAPTMEN1KMT2APYCR1LMNA | |
| SCHEMBL1146137 | 0.84 | MAPT (0.42) | MAPTMEN1KMT2APYCR1LMNA | |
| SCHEMBL1146135 | 0.82 | MAPT (0.41) | MAPTMEN1KMT2APYCR1LMNA | |
| SCHEMBL96044 | 0.78 | TAAR1 (0.50) | MAPTMEN1KMT2APYCR1LMNA | |
| SCHEMBL29818192 | 0.78 | TAAR1 (0.50) | MAPTMEN1KMT2APYCR1LMNA | |
| SCHEMBL8587109 | 0.77 | PYCR1 (0.46) | MAPTMEN1KMT2APYCR1THRB | |
| SCHEMBL11661093 | 0.77 | ESR2 (0.45) | CYP1A2CYP3A4CYP2C9CYP2C19MAPK1 | |
| SCHEMBL11663690 | 0.77 | TRPA1 (0.50) | MAPTMEN1KMT2ALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084824-A | Synthesis method of antidepressant drug, namely voethidine | 万特制药(海南)有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-117924215-A | Synthesis method of vothixetine | 万全万特制药（厦门）有限公司 | 2024-04-26 | — | — | CN | disclosed |