Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.32 |
| ▸ | PIM1 | P11309 | 4/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4354498 | 0.77 | ALDH1A1 (0.41) | PIK3CGPOLBALDH1A1KDM4ETDP1 | |
| SCHEMBL4354444 | 0.74 | PIK3CG (0.37) | PIK3CGPOLBALDH1A1KDM4ETDP1 | |
| SCHEMBL1821874 | 0.74 | TSHR (0.47) | PIK3CGPOLBALDH1A1KDM4ETDP1 | |
| SCHEMBL23284547 | 0.74 | PIK3CG (0.37) | PIK3CGPOLBALDH1A1KDM4ETDP1 | |
| SCHEMBL16402575 | 0.74 | KMT2A (0.37) | PIK3CGPOLBALDH1A1KDM4ETDP1 | |
| SCHEMBL13141437 | 0.71 | PIK3CG (0.35) | PIK3CGPOLBALDH1A1KDM4ETDP1 | |
| SCHEMBL17624323 | 0.70 | — | — | |
| SCHEMBL13683109 | 0.69 | POLB (0.46) | PIK3CGPOLBALDH1A1KDM4ELMNA | |
| SCHEMBL10115593 | 0.69 | — | — | |
| SCHEMBL14043919 | 0.68 | KDM4E (0.38) | PIK3CGPOLBALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924277-A | Oxime ether compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2024-04-26 | — | — | CN | disclosed |