Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | HTR7 | P34969 | 3/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6348675 | 0.79 | CYP11B1 (0.42) | CYP11B1CYP11B2DYRK1ACLK4CYP3A4 | |
| SCHEMBL29196394 | 0.78 | KDM1A (0.50) | CYP2C19 | |
| SCHEMBL29196353 | 0.77 | KDM1A (0.47) | CYP3A4CYP2C19HTR1ALCKCSF1R | |
| SCHEMBL10246359 | 0.76 | LMNA (0.41) | CYP11B1CYP11B2DYRK1ACLK4CYP3A4 | |
| SCHEMBL22912585 | 0.75 | CYP11B1 (0.42) | CYP11B1CYP11B2DYRK1AGRIN1GRIN2B | |
| SCHEMBL13428822 | 0.74 | CD274 (0.41) | CYP11B1CYP11B2DYRK1ACLK4CYP3A4 | |
| SCHEMBL3971719 | 0.74 | LMNA (0.52) | CNR1 | |
| SCHEMBL29694478 | 0.72 | P4HTM (0.51) | CYP11B1CYP11B2DYRK1ACLK4CYP3A4 | |
| SCHEMBL29694479 | 0.72 | P4HTM (0.51) | CYP11B1CYP11B2DYRK1ACLK4CYP3A4 | |
| SCHEMBL28763189 | 0.72 | P4HTM (0.51) | CYP11B1CYP11B2DYRK1ACLK4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924277-A | Oxime ether compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2024-04-26 | — | — | CN | disclosed |