Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | CSF1R | P07333 | 1/20 | 0.51 |
| ▸ | RET | P07949 | 1/20 | 0.51 |
| ▸ | MET | P08581 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.51 |
| ▸ | CDK8 | P49336 | 1/20 | 0.51 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.51 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.51 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28763189 | 1.00 | P4HTM (0.51) | P4HTMAURKAABL1NTRK1LCK | |
| SCHEMBL29694478 | 1.00 | P4HTM (0.51) | P4HTMAURKAABL1NTRK1LCK | |
| SCHEMBL22278915 | 0.91 | P4HTM (0.62) | P4HTMAURKAABL1NTRK1LCK | |
| SCHEMBL22279015 | 0.77 | MAPT (0.49) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6348675 | 0.76 | CYP11B1 (0.42) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL3635563 | 0.76 | ADRA2A (0.49) | P4HTMLMNACYP11B1CYP11B2MAPT | |
| SCHEMBL3636770 | 0.75 | FRK (0.47) | P4HTMAURKAABL1NTRK1LCK | |
| SCHEMBL4740818 | 0.75 | AURKA (0.65) | P4HTMAURKAABL1NTRK1LCK | |
| SCHEMBL29449999 | 0.75 | KDM4E (0.58) | P4HTMAURKAABL1NTRK1LCK | |
| SCHEMBL4738227 | 0.75 | AURKA (0.57) | P4HTMAURKAABL1NTRK1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621202-A | Pyridine amine compound and preparation method and application thereof | 东莞市东阳光农药研发有限公司 | 2022-06-14 | — | — | CN | disclosed |