Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL296312 | 0.86 | HTR7 (0.53) | ALDH1A1KMT2AMEN1CA2POLB | |
| SCHEMBL10428549 | 0.85 | CA2 (0.61) | ALDH1A1KMT2AMEN1CA2POLB | |
| SCHEMBL13111719 | 0.80 | CA2 (0.50) | ALDH1A1KMT2ACA2POLBKDM4E | |
| SCHEMBL6353922 | 0.79 | CA2 (0.48) | ALDH1A1KMT2ACA2POLBKDM4E | |
| SCHEMBL5024938 | 0.79 | TTR (0.55) | ALDH1A1KMT2AMEN1CA2POLB | |
| SCHEMBL31681723 | 0.79 | CA2 (0.48) | ALDH1A1KMT2ACA2POLBKDM4E | |
| SCHEMBL31681724 | 0.79 | TTR (0.55) | ALDH1A1KMT2AMEN1CA2POLB | |
| SCHEMBL5026284 | 0.79 | CA2 (0.48) | ALDH1A1KMT2ACA2POLBKDM4E | |
| SCHEMBL29196369 | 0.77 | SMN1; SMN2 (0.44) | ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1159439 | 0.76 | ATM (0.72) | KMT2AMEN1CA2POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924277-A | Oxime ether compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2024-04-26 | — | — | CN | disclosed |