Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 3/20 | 0.44 |
| ▸ | APLNR | P35414 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30887509 | 1.00 | HTR2A (0.47) | HTR2AKCNH2SLC6A4ARAPLNR | |
| SCHEMBL22481567 | 0.81 | AR (0.47) | HTR2AKCNH2SLC6A4ARTSHR | |
| SCHEMBL30887531 | 0.81 | NR3C1 (0.40) | HTR2AKCNH2SLC6A4MEN1KMT2A | |
| SCHEMBL29196360 | 0.81 | NR3C1 (0.40) | HTR2AKCNH2SLC6A4MEN1KMT2A | |
| SCHEMBL1855982 | 0.80 | AR (0.49) | HTR2AKCNH2SLC6A4ARTSHR | |
| SCHEMBL23755099 | 0.79 | SETDB1 (0.44) | HTR2AKCNH2SLC6A4ARTSHR | |
| SCHEMBL30791546 | 0.79 | SETDB1 (0.53) | HTR2AKCNH2SLC6A4ALDH1A1 | |
| SCHEMBL7667004 | 0.78 | AR (0.47) | HTR2AKCNH2SLC6A4ARTSHR | |
| SCHEMBL3551458 | 0.78 | AR (0.47) | HTR2AKCNH2SLC6A4ARTSHR | |
| SCHEMBL3288455 | 0.78 | AR (0.47) | HTR2AKCNH2SLC6A4ARTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924277-A | Oxime ether compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2024-04-26 | — | — | CN | disclosed |