Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30887531 | 1.00 | NR3C1 (0.40) | NR3C1PGRNR3C2FFAR1FFAR4 | |
| SCHEMBL320376 | 0.83 | LOXL2 (0.50) | NR3C1PGRNR3C2FFAR1FFAR4 | |
| SCHEMBL30887509 | 0.81 | HTR2A (0.47) | KCNH2HTR2ASLC6A4SLC6A3MEN1 | |
| SCHEMBL29196350 | 0.81 | HTR2A (0.47) | KCNH2HTR2ASLC6A4SLC6A3MEN1 | |
| SCHEMBL29506809 | 0.78 | NR3C1 (0.43) | NR3C1PGRNR3C2FFAR1FFAR4 | |
| SCHEMBL3641589 | 0.78 | NR3C1 (0.43) | NR3C1PGRNR3C2FFAR1FFAR4 | |
| SCHEMBL29171043 | 0.78 | FFAR1 (0.39) | NR3C1PGRNR3C2FFAR1FFAR4 | |
| SCHEMBL6077476 | 0.78 | IDO1 (0.48) | P2RX7MEN1KMT2A | |
| SCHEMBL1642300 | 0.75 | FFAR1 (0.48) | NR3C1PGRNR3C2FFAR1FFAR4 | |
| SCHEMBL6942504 | 0.75 | FFAR1 (0.45) | NR3C1PGRNR3C2FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924277-A | Oxime ether compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2024-04-26 | — | — | CN | disclosed |