Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8362649 | 0.87 | HPGD (0.50) | HPGDSTSGPR119EPHX1RECQL | |
| SCHEMBL28694984 | 0.83 | NR1H2 (0.40) | HPGDSTSGPR119 | |
| SCHEMBL897784 | 0.81 | HPGD (0.48) | HPGDSTSGPR119EPHX1RECQL | |
| SCHEMBL29981135 | 0.80 | HPGD (0.54) | HPGDGPR119EPHX1RECQLMAPT | |
| SCHEMBL4008565 | 0.80 | HPGD (0.54) | HPGDGPR119EPHX1RECQLMAPT | |
| SCHEMBL19937755 | 0.77 | MEN1 (0.46) | HPGDSTSGPR119EPHX1MAPT | |
| SCHEMBL22532478 | 0.74 | HPGD (0.49) | HPGDSTSGPR119EPHX1RECQL | |
| SCHEMBL57106 | 0.74 | GPR119 (0.53) | HPGDGPR119EPHX1RECQL | |
| SCHEMBL24572712 | 0.74 | HPGD (0.59) | HPGDGPR119EPHX1RECQLMAPT | |
| SCHEMBL17917077 | 0.74 | USP30 (0.43) | HPGDSTSGPR119EPHX1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117940133-A | Therapeutic agents for degradation of mutant BRAF | C4医药公司 | 2024-04-26 | — | — | CN | disclosed |